Results 291 to 300 of about 3,795,656 (358)

Structurally Modified Polysaccharides: Physicochemical Properties, Biological Activities, Structure-Activity Relationship, and Applications.

Journal of Agricultural and Food Chemistry
Polysaccharides are an important class of biomolecules derived from several sources. However, the inherent structure of polysaccharides prevents them from exhibiting favorable physicochemical properties, which restricts their development in agriculture ...
Yue Chen, Na Zhang, Xiaoqiang Chen
semanticscholar   +1 more source

Structure-activity relationships of adrenocorticotropin

Pharmacology & Therapeutics. Part B: General and Systematic Pharmacology, 1975
Since the entire amino acid sequence of the adrenocort icotropin (adrenocort icotropic hormone, ACTH) from pig pituitaries was proposed (Bell, 1954; Shepherd et al., 1956b), a number of f ragments and analogues of A C T H have been synthesized and submitted to biological characterization.
H, Otsuka, K, Inouye
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Epibatidine Structure—Activity Relationships

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Structure−Activity Relationships of the Didemnins

Journal of Medicinal Chemistry, 1996
Bioactivities of 42 didemnin congeners, either isolated from the marine tunicates Trididemnun solidum and Aplidium albicans or prepared synthetically and semisynthetically, have been compared. The growth inhibition of various murine and human tumor cells and plaque reduction of HSV-1 and VSV grown on cultured mammalian cells were used to assess ...
R, Sakai, K L, Rinehart, V, Kishore, B, Kundu, G, Faircloth, J B, Gloer, J R, Carney, M, Namikoshi, F, Sun, R G, Hughes, D, García Grávalos, T G, de Quesada, G R, Wilson, R M, Heid   +13 more
openaire   +2 more sources

Particle Size Effects in Stoichiometric Methane Combustion: Structure–Activity Relationship of Pd Catalyst Supported on Gamma-Alumina

, 2020
It is an urgent desire to shed insight into the structure–activity relationship of catalysts for stoichiometric methane combustion, a very important reaction in energy utilization and environmental...
Jianjun Chen, Jiawei Zhong, Yang Wu, Weikang Hu, Pengfei Qu, Xin-hong Xiao, Guochen Zhang, Xi Liu, Y. Jiao, Lin Zhong, Yaoqiang Chen   +10 more
semanticscholar   +1 more source

Fuzzy structure-activity relationships

SAR and QSAR in Environmental Research, 2003
While quantitative structure-activity relationships attempt to predict the numerical value of the activities, it is found that statistically good predictors do not always do a good job of qualitatively determining the activity. This study shows how Fuzzy classifiers can be used to generate Fuzzy structure-activity relationships which can more ...
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Quantitative structure-activity relationships

1979
Designing of biologically active molecules on a rational basis is of utmost importance to medicinal chemists. Until about the late 1950’s most of the structure-activity correlations were emperical and qualitative. Although attempts have been made to apply quantitative methods to biological activity since last century, a major effort in this field has ...
A K, Saxena, S, Ram
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Structure–Activity Relationships of Daptomycin Lipopeptides

Journal of Medicinal Chemistry, 2020
Daptomycin is a calcium-dependent cyclic lipodepsipeptide derived from the soil saprotroph Streptomyces roseosporus, and its antibiotic properties make it a key agent for treatment of drug-resistant Gram-positive infections. It is most commonly used clinically for the treatment of Gram-positive skin and skin structure infections (SSSI), Staphylococcus ...
John A. Karas, Glen P. Carter, Benjamin P. Howden, Adrianna M. Turner, Olivia K. A. Paulin, James D. Swarbrick, Mark. A. Baker, Jian Li, Tony Velkov   +8 more
openaire   +3 more sources

Cytochalasins: Structure-activity relationships

Phytochemistry, 1990
Abstract Seven cytochalasins, 17- O -acetylcytochalasin A and two derivatives of cytochalasin B were assayed for Pseudomonas syringae , Bacillus megaterium , and for Geotrichum candidum . Their ability to inhibit the growth of tomato seedlings and their toxicity to brine shrimp (% larvae mortality were also investigated.
Bottalico A, Capasso R, Evidente A, Randazzo G, Vurro M   +4 more
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Structure activity relationships of spiramycins

Journal of Antimicrobial Chemotherapy, 1985
Sixty-six derivatives of spiramycin I and neospiramycin I were synthesized and evaluated by four parameters, MIC, affinity to ribosomes (ID50), therapeutic effect in mice and retention time in HPLC. Among the derivatives, 3,3'',4''-tri-O-propionyl- and 3,4''-di-O-acetyl-3''-O-butyrylspiramycin I showed the highest therapeutic effect which was superior ...
S, Omura, H, Sano, T, Sunazuka
openaire   +2 more sources