Results 61 to 70 of about 314,098 (329)
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Molecules, 2018 Roussoella species are well recorded from both monocotyledons and dicotyledons. As part of a research program to discover biologically active compounds from plant-associated Dothideomycetes in Thailand, the strain Roussoella sp.
Chayanard Phukhamsakda +4 more
doaj +1 more source
Structure elucidation of colibactin [PDF]
, 2019 AbstractColibactin is a gut microbiome metabolite of unknown structure that has been implicated in colorectal cancer formation. Several studies now suggest that the tumorgenicity of colibactin derives from interstrand cross-linking of host DNA. Here we use a combination of genetics, isotope labeling, tandem MS, and chemical synthesis to deduce the ...
Xue, Mengzhao +9 more
openaire +1 more source
Preserving the semantic structure of Islamic key terms and concepts: Izutsu, al-Attas, and al-Raghib al-Isfahani [PDF]
, 2007 This article compares the elucidation of the semantic structure and fixity of a number of key terms and concepts of the Qur'an by two contemporary scholars, Toshihiko Izutsu (1914-1993) and Syed Muhammad Naquib al-Attas (1931--), with that of al-Raghib ...
Arif, Syamsuddin
core
, 2005 Background: With the increase in the number of genome sequencing projects, there is a concomitant exponential growth in the number of protein sequences whose function is still unknown.
MONTI, MARIA +3 more
core +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Isolation and Structure Elucidation of Bis(2-ethylhexyl) terephthalate from barks of Acacia xanthophloea [PDF]
, 2023 Cheloti Michael +9 more
openalex +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Antitumor potential of natural products from marine ascidians of the Gibraltar Strait: A survey
Ciencias Marinas, 2003 The chemical study of a selection of marine ascidians from the Gibraltar Strait has led to the characterization of a collection of natural products of diverse biosynthetic origin.
E Zubía, MJ Ortega, J Salvá
doaj +1 more source
Structure elucidation of ficellomycin.
The Journal of Antibiotics, 1989 The structure of ficellomycin, an antibiotic previously discovered by Argoudelis et al., is elucidated as valyl-2-[4-guanidyl-1-azabicyclo[3.1.0]hexan-2-yl]glycine (1) by NMR, MS, and derivatization studies. The 1-azabicyclo[3.1.0]hexane moiety in 1 represents an unusual ring system making ficellomycin a unique natural product compound.
M S, Kuo, D A, Yurek, S A, Mizsak
openaire +3 more sources