Results 81 to 90 of about 314,098 (329)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Pentacoordination at antimony via endocyclic and exocyclic intramolecular interactions in dibenzostibocine diorganodithiophosphates [{D(C6H4S)2}Sb{S2P(OR)2}] (D=O, S)

Main Group Metal Chemistry, 2013
Treatment of [{D(C6H4S)2}SbCl] (D=O, 1; D=S, 2) with MS2P(OR)2 afforded the stable dibenzostibocine dithiophosphate compounds [{D(C6H4S)2}Sb{S2P(OR)2}] with D=O, R=1,2-C6H4 (3); for D=S, R=1,2-C6H4 (4), Et (5), nPr (6), iPr (7), and Ph (8). The compounds
Alvarado-Rodríguez José G., González-Montiel Simplicio, Andrade-López Noemí   +2 more
doaj   +1 more source

Local Structural Features Elucidate Crystallization of Complex Structures

ACS Nano
38 pages, 6 figures, 80 ...
Maya M. Martirossyan, Matthew Spellings, Hillary Pan, Julia Dshemuchadse   +3 more
openaire   +3 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Isolation of two steroidal saponins with antileishmanial activity from Allium giganteum L.

Research in Pharmaceutical Sciences
Background and purpose: Alliums are rich sources of steroidal saponins, flavonoids, and sulphoric compounds of which steroidal saponins have recently received more attention due to their important pharmacological activities. Allium giganteum (giant onion)
Farnaz Chaparian, Zeinab Delazar, Masoud Sadeghi Dinani   +2 more
doaj   +1 more source

The NMR2 Method to Determine Rapidly the Structure of the Binding Pocket of a Protein–Ligand Complex with High Accuracy

Magnetochemistry, 2018
Structural characterization of complexes is crucial for a better understanding of biological processes and structure-based drug design. However, many protein–ligand structures are not solvable by X-ray crystallography, for example those with low affinity
Marielle Aulikki Wälti, Julien Orts
doaj   +1 more source

Commensurate Nb2Zr5O15: Accessible Within the Field Nb2ZrxO2x+5 After All [PDF]

, 2019
Doped niobium zirconium oxides are applied in field-effect transistors and as special-purpose coatings. Whereas their material properties are sufficiently known, their crystal structures remain widely uncharacterized.
Lerch, Martin, Mühlbauer, Martin J., Orthmann, Steven, Wiedemann, Dennis   +3 more
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Phylogenetic and Chemotaxonomic Studies Confirm the Affinities of Stromatoneurospora phoenix to the Coprophilous Xylariaceae

Journal of Fungi, 2020
The genus Stromatoneurospora was erected in 1973 by Jong and Davis to accommodate the pyrophilic pyrenomycete Sphaeria phoenix and has traditionally been placed in the family Xylariaceae based on morphological features. However, no living culture of this
Kevin Becker, Sarunyou Wongkanoun, Anna-Charleen Wessel, Gerald F. Bills, Marc Stadler, J. Jennifer Luangsa-ard   +5 more
doaj   +1 more source

SOME PHENOLIC COMPOUNDS FROM STEM BARK OF MELINJO (GNETUM GNEMON) AND THEIR ACTIVITY TEST AS ANTIOXIDANT AND UV-B PROTECTION [PDF]

Isolation and structure elucidation of three phenolic compounds, namely 3,4-dimethoxychlorogenic acid (1), resveratrol (2), and 3-methoxyresveratrol (3) from stem bark of Melinjo (Gnetum gnemon) had been done. The isolation of those compounds was carried
Sri , Atun, Ph.D
core