Results 231 to 240 of about 2,132,824 (292)

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Integrated Protein-Lipid Digestion Profiles of Human Milk, Infant Formulas, and Dairy Ingredients Under Infant In Vitro Digestion. [PDF]

Foods
Chen B, Qi Q, Wang X, Zhang X, Zhu X, Yan C, Guan H, Jin R, An Y, Yang J, Xu F, Liu H.   +11 more
europepmc   +1 more source

Spray-Dried Chia Oil Oleogel Microcapsules from Pickering Emulsions: Wall Material Effects on Encapsulation Efficiency and In Vitro Lipid Digestion. [PDF]

Gels
Morales E, Leiva M, Rubilar M, Quilaqueo M, Millao S, Burgos-Díaz C, Hernández-Olivas E.   +6 more
europepmc   +1 more source

Plasma metabolomic signatures of migraine in 479,760 adults. [PDF]

iScience
Hong Y, Chen F, Wang Y, Huang XF.
europepmc   +1 more source

Kinetically Controlled Assembly of Janus-Structured Nanobubble-Lipid Nanoparticles via Ultrasonic Micromixing. [PDF]

Chem Bio Eng
Liu Z, Zhang Y, Chen D, Yang M, Wang L, Jiang H, Du S, Lin J, Chen G.   +8 more
europepmc   +1 more source

Modulation of microbial communication by lipid exudates. [PDF]

ISME J
Gargouri M, Bates PD, Declerck S.
europepmc   +1 more source