Results 41 to 50 of about 3,888,288 (287)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Fostering autonomy in intercultural language learning in the foreign language classroom: A case study of international students learning English at a higher education institution in Ireland [PDF]
, 2012 This study is concerned with the concept of autonomy in intercultural language learning, understood here as the capacity to take responsibility for one’s own language and intercultural development.
Sudhershan, Aleksandra
core +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Teacher education in a flexible higher education environment: Considerations for the future
Teacher Education through Flexible Learning in AfricaAlthough teacher education practices had undergone major changes due to the possibilities that came with developments in the field of information and communication technologies and the introduction of online teaching and learning since the turn of the ...
Lynette Jacobs, Karen Ferreira Meyers
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2019 With this issue, the President’s Student Coucil publication changes its name to President’s Board of Student ...
Naval Postgraduate School +1 more
core +2 more sources
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
COVID-19: Challenges for student recruitment and development [PDF]
, 2020 Findings of the survey looking at employers practice in the recruitment and development of early career hires following the start of the Covid-19 ...
Institute of Student Employers
core
Legal and Ethical Aspects of Teaching Religion in Schools [PDF]
Pharos Journal of TheologyThis study examined the legal and ethical aspects of teaching religion in schools, focusing on how different national education systems balance religious freedom, state neutrality, and inclusivity. Using a comparative legal and ethical analysis approach,
Ermamat Ergeshov
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source