Results 61 to 70 of about 45,086 (261)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

“In their own way”: personalization in history teaching in second-chance academic classes

Frontiers in Education
In this article, I seek to present a case description of personalized learning implemented in my teaching practice as a high school history teacher in central Israel. The study spans two consecutive academic years in two 11th-grade Second-Chance Academic
Oded Cohen, Oded Cohen
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Student - teachers’ self-assessment of their autonomy

Ho Chi Minh City Open University Journal of Science - Social Sciences, 2015
The pilot study presented aims at investigating how student- teachers self-assessed the influence of the portfolio on their autonomy. About 120 student-teachers participated in the portfolio, but only 94 took part in self-assessing their autonomy at the ...
Phan Thi Thu Nga
doaj  

Fostering Intercultural and Entrepreneurial Skills in Undergraduate Music Education: A New Pedagogical Framework

Journal of Applied Science and Engineering
The study focuses on developing a new methodology that would give students the tools they need to participate in the worldwide, digitalized music market as well as integrating intercultural competency and entrepreneurial abilities into undergraduate ...
Qi He, Wei Chen, Dan He
doaj   +1 more source

Teaching quality: High school students’ autonomy and competence

Psicothema, 2018
How teachers manage class learning and interact with students affects students’ motivation and engagement. However, it could be that the effect of students’ representation of teaching quality on the students’ motivation varies between classes.Students from 90 classes participated in the study.
León, Jaime, Medina-Garrido, Elena, Ortega Viera, Miriam   +2 more
openaire   +4 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Learning portfolio (LP) to enhance constructivism and student autonomy

Procedia - Social and Behavioral Sciences, 2010
AbstractA learning portfolio (LP) can be broadly defined as a purposeful collection of student work that exhibits the student's efforts, progress and achievements (Smith & Tillema, 1998). At Preparatory Program at Ozyegin University (hereafter OzU), a new evaluation system is being implemented. This paper describes the components of LP practice at OzU,
Büyükduman, İlke, Dülger, Selen Şirin   +1 more
openaire   +3 more sources