Results 111 to 120 of about 2,203,622 (278)
Specialty preferences among Nigerian medical students: a cross sectional study
Introduction Specialty preferences among medical students significantly influence healthcare workforce distribution and equity. Nigeria, with its low physician-to-patient ratio, faces critical challenges in addressing healthcare demands.
Tobi Olajide+42 more
doaj +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Characterization of the student component in the door-to-door active screening related to COVID-19
Background: the student component in the door-to-door active screening related to COVID-19 is essential for the early detection of positive cases and risk groups.Objective: to characterize the student component in the door-to-door active screening ...
Vladimir Molina-Raad
doaj
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Sexual and Reproductive Health in Rwanda [PDF]
KEY MESSAGES Empowerment (women, youth, communities) Inclusion (age + gender) Prevention/Early Detection PROGRAM RECOMMENDATIONS Partner with Rwandan medical students to improve program delivery Communicate monthly with local leaders Partner with ...
Zhang, Emily
core +1 more source
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla+5 more
wiley +1 more source
Adequate Knowledge and Low Vaccination Rates of Hepatitis B Virus Infection Among Students, Medical, and Paramedical Persons in a Tertiary Care Teaching Hospital. [PDF]
Kandi V+7 more
europepmc +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
OBJECTIVE: To compare the awareness, attitudes towards fertility, and intentions for parenthood between preclinical and clinical medical students. METHODS: An online cross-sectional study was conducted among preclinical and clinical medical students ...
Fehmida Tehsin+2 more
doaj +1 more source
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source