Results 151 to 160 of about 2,018,419 (352)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Bible Theory or Biblical Living: What are Christian Schools Providing for Families with Children with Special Needs?

, 2019
Private Christian elementary and secondary schools, along with Bible training and Bible exercises, have been a part of the United States and international community since the 1800s.
Ramirez, A.Y. Fred, Stymeist, Melissa
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Academic Advisors’ Experiences and Needs Working with Students with Disabilities: A Case of Chiang Mai University

International Journal of Child Development and Mental Health, 2019
The purposes of this research study were to examine 1) advisors’ experiences and needs working with students with disabilities, including awareness of disability issues, individuals’ comfort levels when dealing with various types of disabilities ...
Ratchaneekorn Tongsookdee
doaj  

Criteria and indicators of citizenship of students with special needs [PDF]

, 2011
В статті подано структуру громадянськості студентів з особливими потребами, а також компоненти, критерії і показники її вихованості.The article describes the structure of the citizenship of students with special needs, as well as components, criteria and
Федорова, Є.В.
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Response to Intervention: Implications for use when Identifying Students with Special Needs [PDF]

, 2010
Upon being registered in August of 2006, the Individuals with Disabilities Education Improvement Act (IDEIA) began requiring schools to think about the way in which they identify students with learning disabilities (SLD) and in many cases, then make ...
Harris, Joshua
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Interdependence: Being Reformed by Students with Disabilities

, 2017
Throughout my career in special education, I have reconsidered my beliefs about disability. As I have transitioned from a special educator to a teacher trainer in India to an assistant professor in a Christian college, I have looked beyond limitations ...
Eichhorn, Melinda
core  

Special Education in Catholic Schools Viewed from a Liberatory Hermeneutic [PDF]

, 2019
This study explores anew the issue of providing special education in Catholic schools by viewing the ethical implications from a liberatory hermeneutic.
Carlson, Mary E., LaBelle, Jeffrey
core   +2 more sources