Results 31 to 40 of about 1,601,862 (258)

To Hear Out the Young: The Past and the Future in Two Plays about Komsomol Building Sites [PDF]

open access: yesХудожественная культура
This article focuses on two plays about socialist construction: The City at Dawn (1941), a collective composition by the students of the Moscow State Theatre Studio under the direction of Alexei Arbuzov and Valentin Pluchek, and The Three of Us Went to ...
Mashukova Аlexandra V.
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

L’essor des structures de superviseurs d’effets visuels indépendants en France au XXIe siècle, une nouvelle organisation ?

open access: yesMise au Point
As visual effects developed in France and around the world, a new organization of work was put in place, in line with both technological transformations and the local specificities of the cinema field.
Réjane Hamus-Vallée
doaj   +1 more source

The Magic of the Atelier "Tales of the Rights of the Child"

open access: yesПедагогически форум, 2020
The great French educator of the first half of the 20th century, Celestin Freinet, said that in order to learn something, it must be experienced. The ateliers (workshops), conceived by him as a form of joint practical and creative work of children in ...
Viara Gyurova
doaj   +1 more source

The Educational Green: Researching Ways of Combining Professions [PDF]

open access: yes, 2009
The Educational Green was an innovative 3rd year design studio held in 2007 in the faculty of Architecture, Building and Planning at the University of Melbourne. The studio both informed and was informed by the authors’ involvement in a Research Council (
Hes, Dominique, Wilks, Susan
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Evaluation of Different Housing Typologies with a Design Pedagogy

open access: yesArchitecture
Design studios generally concentrate on some critical concerns of urban life to overcome, and housing is one of those. Rapid development and advanced technology increase the need for and problems with housing. Such concerns should be addressed in theory,
Yalcin Yildirim   +2 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Titien. Actualité des études

open access: yesPerspective, 2008
Titian is an inescapable figure in the history of Venetian painting, casting his shadow over the majority of contemporary artists. Veronese, Tintoretto, and Lotto are often judged in relation to his manierà, and their stylistic characteristics are ...
Guillaume Cassegrain
doaj   +1 more source

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