Results 31 to 40 of about 636,777 (309)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Evaluation of Different Housing Typologies with a Design Pedagogy
ArchitectureDesign studios generally concentrate on some critical concerns of urban life to overcome, and housing is one of those. Rapid development and advanced technology increase the need for and problems with housing. Such concerns should be addressed in theory,
Yalcin Yildirim +2 more
doaj +1 more source
The Magic of the Atelier "Tales of the Rights of the Child"
Педагогически форум, 2020 The great French educator of the first half of the 20th century, Celestin Freinet, said that in order to learn something, it must be experienced. The ateliers (workshops), conceived by him as a form of joint practical and creative work of children in ...
Viara Gyurova
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
And, 2017 House Garibaldi was born by the legend which tells about Garibaldi refugees for a short time in the secret attic of the house. Situated into the Catania historical centre, during the 20 years of Fascism, was the Chamber of Commerce, dance school ...
Studio Gum
doaj
Perspective, 2008 Titian is an inescapable figure in the history of Venetian painting, casting his shadow over the majority of contemporary artists. Veronese, Tintoretto, and Lotto are often judged in relation to his manierà, and their stylistic characteristics are ...
Guillaume Cassegrain
doaj +1 more source
Locating Project Studios and Studio Projects [PDF]
Journal of the Royal Musical Association, 2016 ABSTRACTVia a longitudinal case study of a studio project (Middlewood Sessions, 2004–12), this research explores processes of music-making in the increasingly prevalent context of the project studio to give an insight into contemporary music-making practices.
openaire +2 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Images du Travail, Travail des ImagesThis article presents the results of a quantitative analysis of images showing employees at work featuring on the websites of quebec-based large video game studios (more than 100 employees), in the light of statistics on the socio-demographic profiles ...
Gabrielle Trépanier-Jobin +1 more
doaj +1 more source