Results 41 to 50 of about 1,601,862 (258)

Exploration of Web Technologies: A Real World Application [PDF]

open access: yes, 2016
Our team created a web application for a photography studio. In addition to a portfolio for the studio, the application required the ability to manage photographer schedules, handle and organize orders and provide secure user accounts with different ...
Ballard, Andrew   +2 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Casa Garibaldi

open access: yesAnd, 2017
House Garibaldi was born by the legend which tells about Garibaldi refugees for a short time in the secret attic of the house. Situated into the Catania historical centre, during the 20 years of Fascism, was the Chamber of Commerce, dance school ...
Studio Gum
doaj  

Getting It on Record: Issues and Strategies for Ethnographic Practice in Recording Studios [PDF]

open access: yes, 2014
The recording studio has been somewhat neglected as a site for ethnographic fieldwork in the field of ethno-musicology and, moreover, the majority of published studies tend to overlook the specific concerns faced by the researcher within these contexts ...
Atkinson Paul   +32 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Images de la diversité, de l’équité et de l’inclusion sur les sites Internet des gros studios de jeux vidéo implantés au Québec

open access: yesImages du Travail, Travail des Images
This article presents the results of a quantitative analysis of images showing employees at work featuring on the websites of quebec-based large video game studios (more than 100 employees), in the light of statistics on the socio-demographic profiles ...
Gabrielle Trépanier-Jobin   +1 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Community design studio: a collaboration of architects and psychologists [PDF]

open access: yes, 2005
The 'Community Design Studio' was a programme of collaboration between two courses, one in architecture and the other in environmental psychology. It aimed to generate a creative dialogue identifying responsible and professionally informed plans for the ...
Romice, Ombretta, Uzzell, David
core   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

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