Results 241 to 250 of about 622,021 (312)

Relationship Between Academic Engagement and Social Media Addiction in Ecuadorian University Students. [PDF]

Behav Sci (Basel)
Roque Herrera Y, Alonso García S, Criollo Criollo ADR, López Núñez JA.   +3 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The association between short video addiction and emotion dysregulation among college students: a latent profile analysis and its influencing factors. [PDF]

Front Psychol
Wang S, Liu Z.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The mediating role of social avoidance between relative deprivation and smartphone addiction: a random intercept cross-lagged panel model study. [PDF]

BMC Psychol
Hu W, Zhu Z, Dai Q, Ye B.
europepmc   +1 more source

The influence of digital addiction on adolescents' subjective wellbeing: a meta-analysis. [PDF]

Front Psychol
Zhou J, Chen Z, Wu H, Guan G, Li Y, Kang Y, Sun R, Liu Y.   +7 more
europepmc   +1 more source

The effects of parental psychological control, Internet addiction, anxiety, and depression on online deviant behavior: a latent profile analysis. [PDF]

BMC Psychol
Wang D, Hou Q, Li J, Zhang C.
europepmc   +1 more source