Results 221 to 230 of about 34,885 (296)

To what extent do chickens suffer when gassed with CO₂? [PDF]

Front Vet Sci
Mace JL, Knight A.
europepmc   +1 more source

Impaired Chaperone‐Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation

Advanced Science, EarlyView.
This graphical abstract illustrates how chaperone‐mediated autophagy (CMA) regulates intervertebral disc degeneration (IDD). Under normal homeostasis (B), CMA degrades cytoplasmic Midnolin (MIDN) to maintain proteostasis. Under inflammatory stress (A), impaired CMA leads to cytoplasmic MIDN accumulation.
Xianglong Chen, Haiyang Gao, Wang Wu, Pengzhi Shi, Yuhang Chen, Anran Zhang, Zhangrong Cheng, Wenbo Wu, Zimu Yu, Yukun Zhang   +9 more
wiley   +1 more source

Diagnostic performance of [¹⁸F]Tetrafluoroborate PET versus ¹³¹I scintigraphy in differentiated thyroid cancer: a prospective study. [PDF]

Eur J Nucl Med Mol Imaging
Sonmezoglu K, Sahin OE, Saglam K, Karayel E, Pehlivanoglu H, Uslu-Besli L, Sayman HB.   +6 more
europepmc   +1 more source

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

Advanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai, Xin Mei Zhang, Jing Cheng Zhang, Xu Ting Deng, Qiao Liu, Mustafa Hussein Ali, Fang Zhou Yin, Wu Yin   +7 more
wiley   +1 more source

A review on fueling recovery: the role of metabolic modulation in non-obstructive myocardial stunning. [PDF]

Eur J Med Res
Özkan U, Yalta K, Gürdoğan M, Kounis NG, Altay S.   +4 more
europepmc   +1 more source

Atomistic Kinetics of Dislocation‐Mediated Grain Growth in Monolayer MoS2

Advanced Science, EarlyView.
Atomic‐resolution in‐situ heating microscopy directly visualizes dislocation‐mediated grain boundary migration and grain growth in monolayer MoS2. Mobile grain boundaries migrate through collective motion of Mo 5|7 dislocations, whereas S 5|7 defects remain largely immobile.
Chang‐Won Choi, Min‐Yeong Choi, Tao Du, Jinho Rhee, Seokho Moon, Yeon‐Seo Nam, Xiaoyan Lu, Jong Kyu Kim, Jungwon Park, Moon‐Ho Jo, Cheol‐Joo Kim, Si‐Young Choi   +11 more
wiley   +1 more source

A longitudinal study of woody breast in broiler condemnations and associated risk factors from an Alberta abattoir. [PDF]

Poult Sci
Zhao Y, Mahmood S, Carney V, Uwiera R, Bruce HL.   +4 more
europepmc   +1 more source

Glucose and Glutamine Deprivation Promotes Breast Cancer Lung Metastasis via BRD4‐Dependent Enhancer Activation

Advanced Science, EarlyView.
To model a nutrient‐restricted tumor microenvironment, breast cancer cells were adapted to low glucose and glutamine levels. In the adapted cells, BRD4‐driven enhancer activation increases pro‐invasive EDN1 expression, facilitated by ATF3/c‐JUN and reinforced by enhancer RNA.
Poshan Yugal Bhattarai, Arathy Vasukutty, Yujin Na, Sung‐Chul Lim, Hong Seok Choi   +4 more
wiley   +1 more source

Spontaneous Takotsubo Syndrome and Its Recurrences: Pathogenetic Role of Intraventricular Mechanical Factors. [PDF]

Circ Rep
Yalta K, Ayyıldız G, Ozkan U.
europepmc   +1 more source

Myocardial Stunning Induced by Vasospasm Within an Intercoronary Communication. [PDF]

JACC Case Rep
Mizokami G, Katsuki S, Nakano Y, Oi K, Uwatoku T, Matoba T, Tsutsui H, Abe K.   +7 more
europepmc   +1 more source