Results 151 to 160 of about 14,884,423 (272)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Résonances wagnériennes chez Mario Roso de Luna
, 2001 Contient les textes des communications présentées lors d'une journée d'étude organisée par l'équipe Traverses de l'Université de Paris 8 Vincennes-Saint-Denis.International audienceLa musique comme discours ésotérique pour comprendre l'homme et le ...
Ait Bachir, Nadia
core
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
" Voilà cependant que l'on gagnerait / à prendre le chant pour remède "
, 2013 International audiencePréface du volume "Les contre-ut de la Sibylle. Mythe et Opéra. Séminaires " L'Opéra narrateur " 2011-2012 (Saint-Denis, Université Paris 8-Paris, Institut National d'Histoire de l'Art)".
Faverzani, Camillo
core
Measured resonant wavelengths of an SU-8 integrated photonic microresonator, for temperatures ranging from 3K to room ...
Michal Lipson (1708255) +6 more
core +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
, 2011 Ce volume fait suite à une journée d’études organisée le 27 mars 2010 par l’équipe Genre, Travail et Mobilité du Centre de Recherche Sociologique et Politique de Paris dans le cadre de l’école doctorale Sciences sociales de l’université Paris 8.
Hénaut, Léonie, Bercot, Régine
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Formes d(e l’)Apocalypse: (e-book)
, 2017 International audienceThis online publication collects the proceedings from the international and transdisciplinary conference, “Forms of (the) Apocalypse,” first opus of a series of three (see “Imag(in)ing the Apocalypse,” Brest, March 8-10, 2017 and ...
Michlin, Monica +3 more
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source