Results 21 to 30 of about 93,383 (228)

Sub-acute injection toxicity of Florfenicol VS 30

IOP Conference Series: Earth and Environmental Science, 2021
Abstract This study is aimed at identifying organs and/or target organs systems that are most sensitive to the toxic effect of the drug under study, as well as determining the level of cumulation and reversibility of pathological changes in the animal body influenced by the pharmacological substance.
A V Balyshev, M S Zhuravleva, V V Golovin, S V Abramov, M I Slozhenkina   +4 more
openaire   +1 more source

SUB-ACUTE DERMAL TOXICITY OF SODIUM-CONTAINING DRUGS

Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology, 2023
Drugs that have antimicrobial, anti-inflammatory and wound-healing effects deserve special attention, sodium-containing drugs are one of them, which is why they are used in veterinary medicine. The article presents the results of experimental studies to study the sub-acute toxicity of sodium-containing drugs: known – glycetinate 2%, its analogues
I. Patereha, A. Ostapiuk, V. Kushnir, Ya. Protsyk, O. Pyatnychko, T. Yurynec, M. Chudyak, S. Martynyk   +7 more
openaire   +1 more source

Alternative acute oral toxicity assessment under REACH based on sub-acute toxicity values

ALTEX, 2017
The REACH Regulation requires information on acute oral toxicity for substances produced or imported in quantities greater than one ton per year. When registering, animal testing should be used as last resort. The standard acute oral toxicity test requires use of animals.
Andrea, Gissi, Kimmo, Louekari, Laurence, Hoffstadt, Norbert, Bornatowicz, Alberto Martin, Aparicio   +4 more
openaire   +4 more sources

Acute and sub-acute toxicity studies of roselle leaves

Food Research, 2022
Roselle leaves are widely used in traditional medicine but have not previously been studied for their safety through standard in vivo toxicity studies. This study aimed to evaluate the safety of roselle leaves extract through acute and sub-acute oral toxicity studies in Sprague Dawley (SD) rats.
Hasnisa H., Syahida M., Hadijah H.
openaire   +1 more source

Acute and sub-acute toxicity study of bacterial signaling inhibitor Solanum torvum root extract in Wister rats

Clinical Phytoscience, 2019
Background Solanum torvum root extract is used to treat Asthma, Diabetes, and hypertension by Garo tribal healers of India and Bangladesh. Root tea is used to treat cough and fever by Attapadi tribal people of Kerala, India.
Kayeen Vadakkan
doaj   +1 more source

Acute and subchronic oral toxicity assessments of Combretum micranthum (Combretaceae) in Wistar rats

Toxicology Reports, 2020
Background: Combretum micranthum (CM) (Combretaceae) is widely used in traditional medicine throughout West Africa for the treatment of diabetes, hypertension, inflammation, malaria and liver ailments.
Mabozou Kpemissi, Kossi Metowogo, Mamatchi Melila, Veeresh P. Veerapur, Mihai Negru, Marian Taulescu, Adrian-Valentin Potârniche, Doddamavattur Shivalingaiah Suhas, Tumbadi Adinarayanashetty Puneeth, Sachidananda Vijayakumar, Kwashie Eklu-Gadegbeku, Kodjo Aklikokou   +11 more
doaj   +1 more source

Toxicological evaluation of Bauhinia variegata Linn. for estimating the neurological, hematological and physical alterations in the albino mice

Environment Conservation Journal, 2016
The objective of present study is to establish the safety standards and the evaluation of potential toxicity of Bauhinia variegata Linn. Dried stem bark extract of Bauhinia variegata were evaluated for toxicity studies.
Ashwani Kumar, Vikas Anand2, R.C. Dubey, Kapil K. Goel   +3 more
doaj   +1 more source

Acute and Sub-Chronic Toxicity Study of 1-(2, 5-Dihidroxyphenil)-3- Pyridine-2-Il-Propenone In Adult Female Mice

Indonesian Journal of Pharmacy, 2021
This research aimed to evaluate the toxicity of 1-(2, 5-dihidroxyphenil)-3-pyridine-2-il-propenone (DPP) after 24 hours and 90-day administration in female mice. Acute toxicity test was performed using the OECD 423 method, and DPP was administered once a
Ika Puspitasari, Ratna Asmah Susidarti, Arief Nurrochmad, Pridiyanto Pridiyanto, Devie Amalia Utami, Pipit Febrian, Thoriq Ziyad   +6 more
doaj   +1 more source

Acute and sub-chronic oral toxicity study of purple sweet potato (Ipomoea batatas [L.] Lam) yogurt in mice (Mus musculus) [PDF]

Veterinary World, 2022
Background and Aim: Food safety is an important aspect to be evaluated in preventing any potentially harmful side effects of food product such as yogurt. The purple sweet potato yogurt product was developed to combine the benefits of probiotic activities
Astrid Feinisa Khairani, Yunisa Pamela, Nandina Oktavia, Achadiyani Achadiyani, M. Yusuf Adipraja, Prita Yasri Zhafira, Widad Aghnia Shalannandia, Nur Atik   +7 more
doaj   +1 more source

Preliminary studies of acute and sub-chronic toxicity of the aqueous extract of Guibourtia tessmannii (Harms) J. Leonard stem barks (Caesalpiniaceae) in mice and rats

Asian Pacific Journal of Tropical Biomedicine, 2016
Objective: To investigate the toxicity of aqueous extract of Guibourtia tessmannii (Harms) J. Leonard (G. tessmannii) and evaluate its safety. Methods: NMRI mice were used to determine the acute toxicity of G. tessmannii. Increasing concentrations of the
Noreen Orianna Koumba Madingou, Aristide Traore, Alain Souza, Marlaine Michelle Boukandou Mounanga, Raissa Reine Aworet Samseny, Sylvin Ouedraogo, Alfred Sababenedyo Traore   +6 more
doaj   +1 more source