Results 31 to 40 of about 93,383 (228)

Safety evaluation of enriched fraction from leaves of Dillenia indica L. in BALB/c mice

Toxicology Reports, 2022
The enriched fraction derived from Dillenia indica L. (Dilleniaceae), also known as elephant apple was subjected to acute and sub-acute toxicological study to document its safety issues for use as fumigant. The enriched fractions were orally administered
Kabrambam D. Singh, Sarita Jena, Biswajit Patra, Thiyam B. Devi, Saurabh Chawla, Rupjyoti Bharali, Ajay Parida, Pulok K. Mukherjee, Yallappa Rajashekar   +8 more
doaj   +1 more source

Acute, Sub-Acute and Cell Toxicity of Verbascoside

Research Journal of Medicinal Plant, 2015
Verbascoside or acteoside is the most abundant phenylethanoid glycoside that possesses health beneficial pharmacological activities, including anti-nociceptive, anti-inflammatory and anti-cancer. Due to the wide range of pharmacological activities of verbascoside and insufficient data on the safety profile, the acute, subacute and cellular toxicity of ...
Hossein Hosseinzad, Leila Etemad, Reza Zafari, Naser Vahdati- Mashhadian, Seyed Adel Moallem, Zahra Oskouei Shirvan   +5 more
openaire   +1 more source

TOCOSH FLOUR (Solanum tuberosum L.): A Toxicological Assessment of Traditional Peruvian Fermented Potatoes

Foods, 2020
Potato tocosh is a naturally processed potato for nutritional and curative purposes from traditional Peruvian medicine. The aim of this study was to investigate the acute and sub-acute toxicity of tocosh flour (TF).
Jonas Roberto Velasco-Chong, Oscar Herrera-Calderón, Juan Pedro Rojas-Armas, Renán Dilton Hañari-Quispe, Linder Figueroa-Salvador, Gilmar Peña-Rojas, Vidalina Andía-Ayme, Ricardo Ángel Yuli-Posadas, Andres F. Yepes-Perez, Cristian Aguilar   +9 more
doaj   +1 more source

Investigation of the Biosafety of Antibacterial Mg(OH)₂ Nanoparticles to a Normal Biological System

Journal of Functional Biomaterials, 2023
The toxicity of Mg(OH)2 nanoparticles (NPs) as antibacterial agents to a normal biological system is unclear, so it is necessary to evaluate their potential toxic effect for safe use. In this work, the administration of these antibacterial agents did not
Ying Wang, Yanjing Liu, Xiyue Li, Fuming Wang, Yaping Huang, Yuezhou Liu, Yimin Zhu   +6 more
doaj   +1 more source

Biomarkers of Selenium Toxicity after Sub-Acute Exposure in Mice [PDF]

Journal of Molecular Biomarkers & Diagnosis, 2013
Selenium (Se) is a trace element, essential for human health but it can be toxic at moderately higher intake levels. In this study biomarkers of Se toxicity after sub-acute intra-peritoneal exposure to Se (62.5 µg Se/kg bw/ day; 14 days) were investigated in mice. Such exposure corresponds to high human Se-intake levels. Focus was put on the biomarkers
Jansen, E, Viezeliene, D, Beekhof, P, Gremmer, E, Rodovicius, H, Sadauskiene, I, Ivanov, L   +6 more
openaire   +3 more sources

Toxicological Evaluation of Novel Cyclohexenone Derivative in an Animal Model through Histopathological and Biochemical Techniques

Toxics, 2021
Toxicity studies were conducted to provide safety data of potential drug candidates by determining lethal and toxic doses. This study was designed for pre-clinical evaluation of novel cyclohexenone derivative with respect to the acute and sub-acute ...
Muhammad Kamil, Arifa Fatima, Sami Ullah, Gowhar Ali, Rasool Khan, Naila Ismail, Mughal Qayum, Marius Irimie, Catalina Georgeta Dinu, Hanadi Talal Ahmedah, Maria Elena Cocuz   +10 more
doaj   +1 more source

Transformer mineral oil ingestion induces systemic sub-acute toxicity in Wistar rats. [PDF]

Heliyon, 2019
We investigated the potential toxicities associated with the sub-acute ingestion of transformer mineral oil (TMO) at a heated low dose (HLD-50 mg/kg), heated high dose (HHD-500 mg/kg) and unheated high dose (UHD-500 mg/kg) in Wistar rats. There were increases in red blood cells and haemoglobin levels in HHD females and UHD males respectively versus ...
Otunga GN, Maiyoh GK, Macharia BN, Tuei VC.   +3 more
europepmc   +5 more sources

Sub-acute oral toxicity study with fullerene C60 in rats

The Journal of Toxicological Sciences, 2012
To obtain initial information on the possible repeated-dose oral toxicity of fullerene C60, Crl:CD(SD) rats were administered fullerene C60 by gavage once daily at 0 (vehicle: corn oil), 1, 10, 100, or 1,000 mg/kg/day for 29 days, followed by a 14-day recovery period. No deaths occurred in any groups, and there were no changes from controls in detailed
Mika, Takahashi, Hina, Kato, Yuko, Doi, Akihiro, Hagiwara, Mutsuko, Hirata-Koizumi, Atsushi, Ono, Reiji, Kubota, Tetsuji, Nishimura, Akihiko, Hirose   +8 more
openaire   +3 more sources

Safety of AYUSH OSTO in experimental animals

International Journal of Ayurveda Research
Background: AYUSH OSTO is a coded formulation developed by the Central Council for Research in Ayurvedic Sciences for the treatment of bone-related disorders. Aim: The present study focused on evaluating the safety of AYUSH OSTO through acute, 28-day sub-
Sudesh N. Gaidhani, M. M. Padhi, Arjun Singh, Viswanth Reddy, Srikanth Ala   +4 more
doaj   +1 more source

Phytochemistry and toxicological assessment of Bryonia dioica roots used in north-African alternative medicine

Open Chemistry, 2019
To investigate the phytochemical composition, acute and sub-acute toxicity of the aqueous extract of B. dioica roots. The phytochemical analysis was performed using gas chromatography-mass spectrometry (GC-MS).
Bourhia Mohammed, Bari Ahmed, Ali Syed Saeed, Benbacer Laila, khlil Naima   +4 more
doaj   +1 more source