Results 151 to 160 of about 235,288 (175)

Sub-chronic toxicity of Gyejibokryeong-hwan in Sprague-Dawley rats

Journal of Ethnopharmacology, 2018
Traditional herbal formula Gyejibokryeong-hwan (GJBRH; Guizhifuling-wan, Keishibukuryo-gan) consisting five medicinal herbs has been used to treat uterine disorders, gynecological diseases and blood stasis syndrome in Asia.We evaluated the safety of GJBRH in Crl:CD Sprague-Dawley (SD) rats over a period of 13 weeks.To confirm the stability of the ...
Seong Eun, Jin, Chang-Seob, Seo, Mee-Young, Lee, Hyeun-Kyoo, Shin, Mi-Jin, Yang, Hyekyung, Ha   +5 more
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Sub-chronic oral toxicity of acetamiprid in Wistar rats

Toxicological & Environmental Chemistry, 2015
Acetamiprid is a neoncotinoid insecticide that acts as an agonist to the nicotinic acetylcholine receptor used as insecticide in crops and to control fleas on dogs and cats. The objectives of this study are (1) to evaluate the sub-chronic toxicity of orally administered acetamiprid, (2) to estimate the tissue residue levels and (3) to assess the ...
R.K. Shakthi Devan, Akhilesh Mishra, P.C. Prabu, T.K. Mandal, S. Panchapakesan   +4 more
openaire   +1 more source

The sub-chronic toxicity of a naphthenic hydrocarbon solvent in rats

Regulatory Toxicology and Pharmacology, 2018
Cycloalkanes/naphthenes are constituents of complex hydrocarbon solvents, and hence an understanding of their toxicological profile is critical to establish safe limits for occupational exposures to these solvents. Although naphthenes are structurally related to and share a common metabolic fate with the straight and branched chain analogues, some ...
Juan-Carlos, Carrillo, M David, Adenuga, Fayaz, Momin, Richard H, McKee   +3 more
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Genotoxicity and sub-chronic toxicity of MYOLUTION® (branched chain keto acids)

Regulatory Toxicology and Pharmacology, 2017
MYOLUTION®, which consists of a mixture of the branched chain keto acids, keto-leucine, keto-isoleucine and keto-valine, as their calcium salts, may potentially be used as a food ingredient based on the reported contributions of these compounds to muscle health and exercise performance.
Caroline Hall, Ian Grayson
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Evaluation of acute and sub-chronic oral toxicities of Neoneaster in rats

Journal of Ethnopharmacology, 2023
Jaundice is a condition caused by the elevation of bilirubin level in the blood. Due to the neurological and neurodevelopmental sequalae of jaundice in newborns, the high cost of the treatment, and the side effects of the currently used therapies, novel therapeutically approaches are needed.
Nima Aramipour, Maryam Gholami, Mohammad Saber, Soroor Jafar Gandomi, Naser-Aldin Lashgari, Arash Sadri, Omid Sabzevari   +6 more
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Sub-Chronic Toxicity of Senilia senilis Hepatopancreas in Albino Wistar Mice

Bulletin of Environmental Contamination and Toxicology, 2010
This study investigates the sub-chronic effects of shellfish possibly contaminated by algal toxins in albino Wistar mice. Following in-feed treatment with hepatopancreas, there were significant (p < 0.05) differences in packed cell volume, haemoglobin concentration, red blood cell count, lymphocyte count and alanine aminotransferase between the ...
Okechukwu O, Igboeli, Isaac U, Asuzu
openaire   +2 more sources

Acute and sub-chronic toxicity study of diaveridine in Wistar rats

Regulatory Toxicology and Pharmacology, 2015
Diaveridine, a developed dihydrofolate reductase inhibitor, has been widely used as anticoccidial drug and antibacterial synergist. However, few studies have been performed to investigate its toxicity. To provide detailed toxicity with a wide spectrum of doses for diaveridine, acute and sub-chronic toxicity studies were conducted.
Xu, Wang, Shijia, Su, Awais, Ihsan, Qin, Huang, Dongmei, Chen, Guyue, Cheng, Zhenli, Liu, Yulian, Wang, Zonghui, Yuan   +8 more
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Repeated sub-chronic oral toxicity study of xylooligosaccharides (XOS) in dogs

Regulatory Toxicology and Pharmacology, 2017
In this study, Beagle dogs were administered xylooligosaccharide (XOS, CAS # 87099-0) at doses of 0, 1250, 2500, and 5000 mg/kg/day by oral gavage for 26 weeks. A 4-week recovery period was added to observe delayed or reversible toxicity. Measurements included body weight, food consumption, clinical observations, temperature, electrocardiogram (ECG ...
Yonglin, Gao, Yunzhi, Wang, Yanshen, Li, Rui, Han, Chunmei, Li, Lin, Xiao, Susan, Cho, Yukui, Ma, Chao, Fang, Albert W, Lee   +9 more
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Acute and sub-chronic toxicity of four cytostatic drugs in zebrafish

Environmental Science and Pollution Research, 2015
The acute and sub-chronic effects of four cytostatic drugs-5-fluorouracil (5-FU), cisplatin (CisPt), etoposide (ET) and imatinib mesylate (IM)-on zebrafish (Danio rerio) were investigated. Acute tests were carried out in a static system in accordance with the OECD guideline 203 for adult fish and the draft guideline for fish embryos (FET test) in order
Róbert Kovács, Katalin Bakos, Béla Urbányi, Judit Kövesi, Gyöngyi Gazsi, Andrea Csepeli, Ádám János Appl, Dóra Bencsik, Zsolt Csenki, Ákos Horváth   +9 more
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Acute and Sub-Chronic Toxicity ofD-Allose in Rats

Bioscience, Biotechnology, and Biochemistry, 2010
We examined the acute and sub-chronic toxicity of D-allose in rats. In the acute toxicity test, the calculated LD(50) value was 20.5 g/kg. In the sub-chronic toxicity test, no difference was found among the four groups in most of the serum chemical and hematological test results. These results suggest that D-allose is not toxic to rats.
Yusuke, Iga, Kazunori, Nakamichi, Yoko, Shirai, Tatsuhiro, Matsuo   +3 more
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