Results 21 to 30 of about 36,100 (249)

Microdrilling Resulted in Less Subchondral Bone Destruction Than a Traditional Microfracture Awl for Articular Cartilage Defect Bone Marrow Stimulation

Arthroscopy, Sports Medicine, and Rehabilitation, 2023
Purpose: The purpose of this study was to compare bone marrow stimulation using micro-computed tomography (micro-CT) analysis of an abrasion arthroplasty technique, drilling k-wire technique, traditional microfacture awl, or a microdrill instrument for ...
Lucy E. Meyer, M.D., Richard M. Danilkowicz, M.D., Zoe W. Hinton, M.D., Bryan S. Crook, M.D., Bijan Abar, M.H.S., Nicholas B. Allen, B.S., Mitchell Negus, B.S.E., Eoghan T. Hurley, M.B., M.Ch., Ph.D., Alison P. Toth, M.D., Annunziato Amendola, M.D., Samuel B. Adams, M.D.   +10 more
doaj   +1 more source

Osteo-core plasty: minimally invasive approach for subchondral pathologies

Journal of Cartilage & Joint Preservation, 2023
The subchondral bone is a critical part of the osteochondral unit, providing nutrients to the overlying articular cartilage, thereby maintaining viability of the chondral tissue.
Katarzyna Herman, Graeme P. Whyte, Anna Montagna, Leandra Bizzoco, Nogah Shabshin, Dawid Szwedowski, Alberto Gobbi   +6 more
doaj   +1 more source

Semiquantitative assessment of subchondral bone marrow edema-like lesions and subchondral cysts of the knee at 3T MRI: A comparison between intermediate-weighted fat-suppressed spin echo and Dual Echo Steady State sequences

BMC Musculoskeletal Disorders, 2011
Background Choice of appropriate MR pulse sequence is important for any research studies using imaging-derived data. The aim of this study was to compare semiquantitative assessment of subchondral bone marrow edema-like lesions and subchondral cysts ...
Jakicic John M, Moore Carolyn, Hannon Michael J, Kwoh C Kent, Guermazi Ali, Hayashi Daichi, Green Stephanie M, Roemer Frank W   +7 more
doaj   +1 more source

Defactinib attenuates osteoarthritis by inhibiting positive feedback loop between H-type vessels and MSCs in subchondral bone

Journal of Orthopaedic Translation, 2020
Summary: Background: Abnormal bone formation in subchondral bone resulting from uncoupled bone remodeling is considered a central feature in osteoarthritis (OA) pathogenesis. H-type vessels can couple angiogenesis and osteogenesis.
Yanjun Hu, Hangtian Wu, Ting Xu, Yutian Wang, Hanjun Qin, Zilong Yao, Peisheng Chen, Yongheng Xie, Zhiguo Ji, Kaifan Yang, Yu Chai, Xianrong Zhang, Bin Yu, Zhuang Cui   +13 more
doaj   +1 more source

Exercise improves subchondral bone microenvironment through regulating bone-cartilage crosstalk

Frontiers in Endocrinology, 2023
Articular cartilage degeneration has been proved to cause a variety of joint diseases, among which osteoarthritis is the most typical. Osteoarthritis is characterized by articular cartilage degeneration and persistent pain, which affects the quality of ...
Shihua Zhang, Shihua Zhang, Tingting Li, Yao Feng, Keping Zhang, Jun Zou, Xiquan Weng, Yu Yuan, Lan Zhang, Lan Zhang   +9 more
doaj   +1 more source

Bibliometric insights from publications on subchondral bone research in osteoarthritis

Frontiers in Physiology, 2022
Background: The role of subchondral bone in the pathogenesis of osteoarthritis has received continuous attention worldwide. To date, no comprehensive bibliometric analysis of this topic has been carried out.
Pengfei Wen, Rui Liu, Jun Wang, Yakang Wang, Wei Song, Yumin Zhang   +5 more
doaj   +1 more source

Subchondral osteoclasts and osteoarthritis: new insights and potential therapeutic avenues

Acta Biochimica et Biophysica Sinica
Osteoarthritis (OA) is the most common joint disease, and good therapeutic results are often difficult to obtain due to its complex pathogenesis and diverse causative factors.
Chen Wenlong, Wang Qiufei, Tao Huaqiang, Lu Lingfeng, Zhou Jing, Wang Qiang, Huang Wei, Yang Xing   +7 more
doaj   +1 more source

Subchondral bone deterioration in femoral heads in patients with osteoarthritis secondary to hip dysplasia: A case–control study

Journal of Orthopaedic Translation, 2020
Objectives: Residual hip dysplasia is the most common underlying condition leading to secondary osteoarthritis (OA) of the hip. Subchondral bone alterations in OA secondary to hip dysplasia (HD-OA) are poorly investigated.
Guangyi Li, Lianzhi Chen, Qiujian Zheng, Yuanchen Ma, Changqing Zhang, Ming Hao Zheng   +5 more
doaj   +1 more source

Distinct pathological changes of osteochondral units in early OVX-OA involving TGF-β signaling

Frontiers in Endocrinology, 2022
IntroductionDifferent opinions exist about the role of subchondral bone in osteoarthritis (OA), probably because subchondral bone has different effects on cartilage degeneration in OA induced by different pathologies.
Zihuan Yang, Qizhao Tan, Zhenda Zhao, Guodong Niu, Siwei Li, Siwei Li, Weishi Li, Weishi Li, Chunli Song, Chunli Song, Huijie Leng   +10 more
doaj   +1 more source

A three-dimensional printed porous implant combined with bone grafting following curettage of a subchondral giant cell tumour of the proximal tibia: a case report

BMC Surgery, 2019
Background Subchondral bone is commonly affected in cases of giant cell tumour (GCT) of the proximal tibia. Numerous studies have stated that retaining a sufficient subchondral bone layer could decrease the possibilities of postoperative degenerative ...
Minxun Lu, Jie Wang, Fan Tang, Li Min, Yong Zhou, Wenli Zhang, Chongqi Tu   +6 more
doaj   +1 more source