Results 71 to 80 of about 36,100 (249)

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

A prospective follow up of age related changes in the subchondral bone density of the talus of healthy Labrador Retrievers

BMC Veterinary Research, 2017
Background During growth, the skeletal structures adapt to the increased loading conditions and mature to a fully-grown skeleton. Subchondral bone density reflects the effect of long-term joint loading and it is expected to change over time.
W. Dingemanse, M. Müller-Gerbl, I. Jonkers, J. Vander Sloten, H. van Bree, I. Gielen   +5 more
doaj   +1 more source

High‐Resolution Deep Learning Dixon Magnetic Resonance Imaging of the Sacroiliac Joints Is Noninferior to Standard Magnetic Resonance Imaging in Patients With Suspected Axial Spondyloarthritis

Arthritis &Rheumatology, EarlyView.
Objective To compare the multisequence standard magnetic resonance imaging (sMRI) protocol of the sacroiliac joints with a single high‐resolution deep learning–reconstructed Dixon sequence (DL‐Dixon) in patients with suspected axial spondyloarthritis (axSpA). Methods Seventy‐six patients with chronic low back pain and suspected axSpA underwent clinical,
Dominik Deppe, Mariam Koka, Fabian Proft, Sevtap Tugce Ulas, Kay‐Geert Hermann, Denis Poddubnyy, Mikhail Protopopov, Henriette Baum, Hildrun Haibel, Mehrgan Shahryari, Valeria Rios Rodriguez, Jens Vogel‐Claussen, Torsten Diekhoff   +12 more
wiley   +1 more source

Decrease in Local Volumetric Bone Mineral Density in Osteoarthritic Joints Is Associated with the Increase in Cartilage Damage: A Peripheral Quantitative CT Study

Frontiers in Materials, 2017
Osteoarthritis (OA) is one of the most prevalent joint diseases, which causes pain and disability in the adult population. OA affects the osteochondral unit in the joints, which comprises both cartilage and subchondral bone.
Maryam Tamaddon, Shen Mao Chen, Leyre Vanaclocha, Alister Hart, Alister Hart, Moataz El-Husseiny, Johann Henckel, Chaozong Liu   +7 more
doaj   +1 more source

Surgical Technique for Treating Focal Osteochondral Knee Lesions Using an Aragonite‐Based Biphasic Scaffold

Arthroscopy Techniques, EarlyView.
Abstract Osteochondral lesions of the knee, particularly in patients with early osteoarthritic changes, remain a clinical challenge. The Agili‐C implant (CartiHeal, Smith & Nephew), an aragonite‐based osteochondral scaffold, offers a single‐stage, off‐the‐shelf solution designed to regenerate both cartilage and subchondral bone.
Eric Wang, Alexandra M. Cancio‐Bello, Katelyn T. Koschmeder, Bryn Berens, Anikar Chhabra   +4 more
wiley   +1 more source

Fresh Talus Allograft Preparation for the Treatment of a Large Off‐Track Hill‐Sachs Lesion

Arthroscopy Techniques, EarlyView.
Abstract Large off‐track Hill‐Sachs lesions present a significant challenge in the management of recurrent anterior shoulder instability, particularly in young, active patients. Traditional Hill‐Sachs management procedures include remplissage, coracoid transfer and free bone block reconstruction, which all carry associated limitations, including non ...
Michael J. Nocek, Mikalyn T. DeFoor, Taylor Calibo, Nate J. Dickinson, Madeleine Blankenship, Matthew T. Provencher   +5 more
wiley   +1 more source

Combined Medial Unicompartmental Knee Arthroplasty and Revision Allograft Anterior Cruciate Ligament Reconstruction

Arthroscopy Techniques, EarlyView.
Abstract Combined medial unicompartmental knee arthroplasty and revision anterior cruciate ligament reconstruction with an Achilles tendon allograft offers a promising solution for young, active patients with isolated medial compartment osteoarthritis and a failed prior anterior cruciate ligament reconstruction.
Ryan J. Froom, Alexi J. Panos, Molly E. Kessenich, Nate Dickinson, Mikalyn T. DeFoor, Nathan Cafferky, Matthew T. Provencher   +6 more
wiley   +1 more source

Biceps‐Augmented Reverse Remplissage for Filling of Reverse Hill‐Sachs Defects

Arthroscopy Techniques, EarlyView.
Abstract Reverse Hill‐Sachs lesions pose a complex challenge in the management of posterior shoulder dislocations. These lesions complicate surgical management as a result of their association with recurrent instability and further joint destruction.
Mohamed Gamal Morsy, Ahmed Rafat Nageeb Abdelhakim, Hesham Mohamed Gawish   +2 more
wiley   +1 more source

Arthroscopic Implantation of Minced Cartilage From the Os Trigonum and Posterolateral Process of the Talus: Single‐Stage Cell‐Based Treatment of Osteochondral Lesion of the Talus

Arthroscopy Techniques, EarlyView.
Abstract The best surgical treatment of osteochondral lesion of the talus (OLT) remains controversial. Among the available surgical procedures for OLTs, implantation of the minced cartilage from the talar lesion is a promising cell‐based technique. However, surgeons may experience difficulties when enough volume and quality of the cartilage cannot be ...
Hélder Pereira, Takuji Yokoe
wiley   +1 more source

Rimplasty: An Arthroscopic Technique for Patients With Isolated Patellar Chondromalacia Based on Autologous Matrix‐induced Chondrogenesis+ and Limited Trochleoplasty

Arthroscopy Techniques, EarlyView.
Abstract Anterior knee pain is a common problem that can be difficult to treat. One potential cause of these symptoms is supratrochlear rim, which has been linked to isolated patellar chondromalacia in patients with patella alta and without any history of patellar dislocation or subluxation.
Tomasz Piontek, Bartosz Bąbik, Jakub Bąbik, Artur Banach   +3 more
wiley   +1 more source