Results 51 to 60 of about 699,373 (191)

Efficacy of Subconjunctival Injection of Bevacizumab in Regressing Corneal Neovascularisation

Journal of the College of Physicians and Surgeons Pakistan, 2019
To determine the efficacy of subconjunctival injection of bevacizumab in regressing corneal neovascularisation.Case series.Department of Ophthalmology, Chandka Medical College and Hospital, SMBBMU, Larkana, Pakistan, from October 2015 to March 2016.A total of 95 patients with corneal neovascularisation of more than 3 months' duration and with no ...
openaire   +2 more sources

Innovative Drug Delivery Systems for the Treatment of Glaucoma

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu, Junzhi Li, Zhenlin Chen, Jinyu Zhang, Siqi Feng, Jiaying Huang, Yawen Chu, Xue Zhou, Wei Wang, Shangsi Chen   +9 more
wiley   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, Volume 4, Issue 1, March 2026.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Repeated bevacizumab injections versus mitomycin C in rotational conjunctival flap for prevention of pterygium recurrence

Indian Journal of Ophthalmology, 2014
Aims: To evaluate the efficacy of repeated bevacizumab injection in rotational conjunctival flap surgery versus rotational conjunctival flap with adjunctive mitomycin C (MMC) or rotational conjunctival flap alone. Materials and Methods: Ninety eyes of 90
Mustafa Ozsutcu, Emre Ayintap, Julide C U Akkan, Arif Koytak, Cengiz Aras   +4 more
doaj   +1 more source

EFFECT OF BEVACIZUMAB ON α-SMOOTH MUSCLE ACTIN EXPRESSION AND FIBROBLAST COUNT IN TRABECULECTOMY AREA TOWARDS PREVENTION OF FIBROSIS

Journal of Stem Cell Research and Tissue Engineering, 2022
Objective to analyze the effect of bevacizumab on α-smooth muscle actin expression and fibroblast count in trabeculectomy area of rabbit models in order to find a safer modulator of wound healing to improve surgical outcome.
Sekar Ayu Sitoresmi Sekar Ayu
doaj   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Role of Anti VEGF Agent in Management of Primary Pterygium

Delhi Journal of Ophthalmology, 2018
Objective: To assess the role of Anti VEGF agent in management of primary pterygium. Study Design: Prospective Study. Methodology: This prospective comparative study included twenty (20) eyes with primary nasal pterygium and off label use of a single ...
Abhinav Singh, Sagarika Patyal, Vinod K. Baranwal, Gaurav Kapoor   +3 more
doaj   +1 more source

Mass spectrometry in ocular drug research

Mass Spectrometry Reviews, Volume 45, Issue 1, Page 37-68, January/February 2026.
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo, Kati‐Sisko Vellonen, Arto Urtti, Tetsuya Terasaki, Anam Hammid, Paavo Honkakoski, Seppo Auriola   +6 more
wiley   +1 more source

Subconjunctival Injection of Bevacizumab (Avastin) on Corneal Neovascularization in Different Rabbit Models of Corneal Angiogenesis

, 2011
PURPOSE. Bevacizumab is a potent recombinant humanized monoclonal antibody directed against vascular endothelial growth factor (VEGF). The purpose of this study was to evaluate the therapeutic effect of subconjunctival injection of bevacizumab on corneal
CHEN, WEI-LI;LIN, CHUNG-TIEN;LIN, NIEN-TING;TU, I-HUA;CHOW, LU-PING;LIU, KWAN-RONG;HU, FUNG-RONG, 陳偉勵;林中天;林念庭;杜怡樺;周綠蘋;劉寬鎔;胡芳蓉   +1 more
core   +1 more source

Comparison of the effects of subconjunctival and topical anti-VEGF therapy (bevacizumab) on experimental corneal neovascularization [PDF]

, 2014
Purpose: To compare the effects of bevacizumab applied either subconjunctivally or topically, in a rat model of corneal neovascularization induced by alkali burn. Methods: The right corneas of 24 Wistar-Albino rats were cauterized with silver nitrate
Cigdem Akdag (5765054), Ozgul Altintas (5765045), Ozdemir Ozdemir (5762834), Levent Altintas (5765048), Berna Ozkan (5765051), Nurşen Yüksel (807872)   +5 more
core   +1 more source