Results 171 to 180 of about 312,772 (298)

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source

Application of Nanoparticles for Immunotherapy of Allergic Rhinitis

International Journal of Nanomedicine
Kaiqiang Li,1,2,* Jing Jin,3,* Yimin Yang,4,* Xuling Luo,4 Yaling Wang,1 Aibo Xu,1 Ke Hao,1,2 Zhen Wang1,2 1Laboratory Medicine Center, Allergy Center, Department of Transfusion Medicine, Zhejiang Provincial People’s Hospital (Affiliated ...
Li K, Jin J, Yang Y, Luo X, Wang Y, Xu A, Hao K, Wang Z   +7 more
doaj  

Monitoring adherence and patient-reported outcomes during subcutaneous immunotherapy for house dust mites with the AllergyVax app/web platform. [PDF]

J Allergy Clin Immunol Glob
Aarestrup MF, Monteiro Aarestrup F, Aarestrup PF, Aarestrup BJV, Cheloni Aarestrup EP, Nagato AC, Amaral Correa JO.   +6 more
europepmc   +1 more source

House dust mite subcutaneous immunotherapy has sustained long-term effectiveness on allergic rhinitis and asthma: A 10-year follow-up. [PDF]

Immun Inflamm Dis, 2023
Rodriguez-Plata E, Callero Viera A, Ruiz-Garcia M, Gomez-Cardenosa A, Nieto E, García-Robaina JC.   +5 more
europepmc   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Identifying Causes of Subcutaneous Immunotherapy Non-Adherence in Patients with Allergic Rhinitis: A Cross-Sectional Study. [PDF]

Patient Prefer Adherence
Huang CZ, Tang ZY.
europepmc   +1 more source

Effects of house dust mite subcutaneous immunotherapy in real-life. Immunological and clinical biomarkers and economic impact analysis. [PDF]

World Allergy Organ J, 2023
Caruso C, Colantuono S, Tolusso B, Di Mario C, Fancello G, La Sorda M, Celi G, Caringi M, Volterrani A, Descalzi D, Gremese E, Sanguinetti M, Gasbarrini A, Canonica GW.   +13 more
europepmc   +1 more source

PROTAC‐Engineered Protein/DNA Nanoantigen is a Potent Booster for Dendritic Cell Vaccines in Cancer Immunotherapy

Advanced Science, EarlyView.
A PROTAC‐functionalized protein/DNA‐integrated nanoantigen platform is developed to enhance dendritic cell vaccine potency. By combining a VHL‐recruiting peptide‐modified antigen with a sustained expression plasmid within CaCO3 nanoparticles, this system amplifies cross‐presentation, promotes DC maturation, and elicits robust Th1 and CTL responses ...
Peng Liu, Qiang Chen, Zhe Zhou, Yuekang Xu, Jinyao Li   +4 more
wiley   +1 more source

Clinical evaluation of long-term efficacy of house dust mite subcutaneous immunotherapy in children with allergic asthma. [PDF]

Transl Pediatr
Tang Y, Zhao R, Li F, Dong N, Yuan L, Wang C, Zhu S, Dong X.   +7 more
europepmc   +1 more source

Clinical response to subcutaneous immunotherapy at 3 years in allergic rhinitis patients is predicted by short-term treatment effectiveness. [PDF]

Clin Transl Allergy, 2023
Liu D, Li J, Gao Y, Cao F, Xiong W, Wang C, Zhang Y, Zhang L.   +7 more
europepmc   +1 more source