Results 41 to 50 of about 3,372 (201)
Autoimmunity related to anti-Nax and anti-ZSCAN1 autoantibodies in adipsic hypernatremia
Endocrine Journal“Adipsic hypernatremia” is clinically characterized by chronic elevation of plasma [Na+] with an inappropriate lack of thirst and upward resetting of the osmotic set point for arginine vasopressin (AVP) secretion, combined with a relative deficiency of ...
Akari Nakamura-Utsunomiya
doaj +1 more source
A preliminary study of the effect of a high-salt diet on transcriptome dynamics in rat hypothalamic forebrain and brainstem cardiovascular control centers [PDF]
PeerJ, 2020 Background High dietary salt intake is strongly correlated with cardiovascular (CV) diseases and it is regarded as a major risk factor associated with the pathogenesis of hypertension.
Chitra Devi Ramachandran +3 more
doaj +2 more sources
Lectin-Binding Glycoconjugates in the Subfornical Organ of the Rat
Okajimas Folia Anatomica Japonica, 1997 In the rat subfornical organ (SFO), lectin-binding glycoconjugates were histochemically examined by 9 biotinylated lectins using a streptavidin-biotin peroxidase system. The strong or moderate binding of Canavalia ensiformis (Con A), Lens culinaris (LCA) and Phaseolus vulgaris erythroagglutinin (ePHA) indicated overall distributions of high mannose ...
UEDA, Takashi +2 more
openaire +3 more sources
Expression of certain proteins in the subfornical organ and cerebrospinal fluid of spontaneously hypertensive rats [PDF]
, 2007 The objective of this study was to analyze the proteins in the cerebrospinal fluid of spontaneously hypertensive rats and to study their possible role in the relationship between hydrocephalus, arterial hypertension and variations in the subfornical ...
Castañeyra-Ruíz, L. +10 more
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Interpreting Anxiety Disorders From the Perspective of Interoceptive Computational Models
Brain and Behavior, Volume 15, Issue 12, December 2025.Pathological anxiety stems from computational failures in interoception, where rigid threat beliefs amplify prediction errors. This review outlines how these mechanisms sustain maladaptive behaviors and cognitive biases. We synthesize a path forward by integrating computational models with targeted interventions to recalibrate this dysregulated process
Zihan Lin +6 more
wiley +1 more source
A kidney-brain neural circuit drives progressive kidney damage and heart failure
Signal Transduction and Targeted Therapy, 2023 Chronic kidney disease (CKD) and heart failure (HF) are highly prevalent, aggravate each other, and account for substantial mortality. However, the mechanisms underlying cardiorenal interaction and the role of kidney afferent nerves and their precise ...
Wei Cao +8 more
doaj +1 more source
Brain Research Bulletin, 2022 The perinatal environment interacts with the genotype of the developing organism resulting in a unique phenotype through a developmental or perinatal programming phenomenon.
F.M. Dadam +3 more
doaj +1 more source
Am J Physiol Heart Circ Physiol, 2017 In systolic heart failure (HF), circulating proinflammatory cytokines upregulate inflammation and renin-angiotensin system (RAS) activity in cardiovascular regions of the brain, contributing to sympathetic excitation and cardiac dysfunction.
Yu Y, Wei SG, Weiss RM, Felder RB.
europepmc +2 more sources
Cellular mechanisms of long‐term osmoregulation in magnocellular neurons
Journal of Neuroendocrinology, Volume 37, Issue 12, December 2025.Abstract Osmoregulation is an essential homeostatic process that maintains the osmolality of the extracellular fluid (ECF) close to a physiological setpoint. Vasopressin (VP) plays a key role in osmoregulation and is secreted by the magnocellular neurosecretory cells (MNCs) of the hypothalamus.
Kirk D. Haan, Thomas E. Fisher
wiley +1 more source
Am J Physiol Regul Integr Comp Physiol, 2017 Direct intracerebroventricular injection of angiotensin II (ANG II) causes increases in blood pressure and salt and water intake, presumably mimicking an effect mediated by an endogenous mechanism.
Agassandian K +6 more
europepmc +2 more sources