Results 51 to 60 of about 608,087 (203)
Thirst and blood pressure regulation in a novel angiotensin II receptor type 1a knockout rat
Physiological Reports, Volume 14, Issue 15, August 2026.Regulation of arterial blood pressure (ABP) is largely preserved in angiotensin II receptor 1a knock‐out (Agtr1a−/−) rats. However, deletion of Agtr1a attenuates thirst in response to AngII and hypotension but not intracellular dehydration. Abstract Angiotensin II (AngII) plays a pivotal role in body fluid balance through AngII type 1 receptors (Agtr1)
Caroline B. Ferreira, Sean D. Stocker
wiley +1 more source
Sniffer cells for the detection of neural Angiotensin II in vitro
Scientific Reports, 2019 Neuropeptide release in the brain has traditionally been difficult to observe. Existing methods lack temporal and spatial resolution that is consistent with the function and size of neurons.
George E. Farmer +5 more
doaj +1 more source
A kidney-brain neural circuit drives progressive kidney damage and heart failure
Signal Transduction and Targeted Therapy, 2023 Chronic kidney disease (CKD) and heart failure (HF) are highly prevalent, aggravate each other, and account for substantial mortality. However, the mechanisms underlying cardiorenal interaction and the role of kidney afferent nerves and their precise ...
Wei Cao +8 more
doaj +1 more source
Brain Research Bulletin, 2022 The perinatal environment interacts with the genotype of the developing organism resulting in a unique phenotype through a developmental or perinatal programming phenomenon.
F.M. Dadam +3 more
doaj +1 more source
Lectin-Binding Glycoconjugates in the Subfornical Organ of the Rat
Okajimas Folia Anatomica Japonica, 1997 In the rat subfornical organ (SFO), lectin-binding glycoconjugates were histochemically examined by 9 biotinylated lectins using a streptavidin-biotin peroxidase system. The strong or moderate binding of Canavalia ensiformis (Con A), Lens culinaris (LCA) and Phaseolus vulgaris erythroagglutinin (ePHA) indicated overall distributions of high mannose ...
UEDA, Takashi +2 more
openaire +3 more sources
Journal of Neuroendocrinology, Volume 38, Issue 7, July 2026.Calbindin 1 marks fluorogold‐positive magnocellular oxytocin neurons and a subset of magnocellular vasopressin neurons, whereas reelin marks a subset of fluorogold‐negative parvocellular oxytocin neurons. Abstract Oxytocin (OXT)‐ and arginine vasopressin (AVP)‐synthesizing neurons are traditionally classified into magnocellular and parvocellular types ...
Naranbat Nasanbuyan +4 more
wiley +1 more source
Modulation of subfornical organ neurons by neurotensin [PDF]
, 2023 Neurotensin (NT) is a 13 amino-acid peptide which is both a hormone and neuromodulator. Through its 3-4 known receptors, NT is shown to influence several physiological responses including autonomic output, hydromineral balance, and cardiovascular ...
Belyea, M Megan
core
Fluids and Barriers of the CNS, 2012 Background Hydrocephalus is a heterogeneous disorder with multiple etiologies that are not yet fully understood. Animal models have implicated dysfunctional cilia of the ependyma and choroid plexus in the development of the disorder.
Swiderski Ruth E +5 more
doaj +1 more source
Addiction Biology, Volume 31, Issue 4, April 2026.AT1R signaling drives addiction through interconnected pathways, and AT1R antagonists target multiple nodes for therapeutic effects. ABSTRACT Although the angiotensin II type 1 receptor (AT1R), a pivotal component of the renin–angiotensin system (RAS), is associated with cardiovascular and renal homeostasis, burgeoning evidence implicates its critical ...
Jianan Lv +7 more
wiley +1 more source
Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications
Experimental Physiology, Volume 111, Issue 3, Page 653-673, 1 March 2026.Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó +1 more
wiley +1 more source