Isolation, Molecular Characterisation, and Pathogenicity Analysis of a Novel Recombinant ALV-J Strain Isolated From Chinese Hetian Chickens. [PDF]
Reduced mortality: The isolated LY2021J strain of ALV‐J from Hetian chickens showed lower mortality despite causing severe dysplasia. Genetic similarity: LY2021J exhibited high genetic similarity to the Chinese Heilongjiang strain JS14NT01, particularly in the gp85 and pol genes, suggesting a possible common origin.
Lei T +7 more
europepmc +2 more sources
Domestic chickens activate a piRNA defense against avian leukosis virus [PDF]
PIWI-interacting RNAs (piRNAs) protect the germ line by targeting transposable elements (TEs) through the base-pair complementarity. We do not know how piRNAs co-evolve with TEs in chickens.
Anai +124 more
core +2 more sources
A Genetically Engineered Commercial Chicken Line Is Resistant to Highly Pathogenic Avian Leukosis Virus Subgroup J [PDF]
Viral diseases remain a major concern for animal health and global food production in modern agriculture. In chickens, avian leukosis virus subgroup J (ALV-J) represents an important pathogen that causes severe economic loss.
Bertzbach, Luca D. +11 more
core +1 more source
Glycogen synthase kinase 3β (GSK3β) is a widely distributed multifunctional serine/threonine kinase. In mammals, GSK3β regulates important life activities such as proinflammatory response, anti-inflammatory response, immunity, and cancer development ...
Zhouhao Cui +6 more
doaj +1 more source
Immunological basis of differences in disease resistance in the chicken [PDF]
Genetic resistance to diseases is a multigenic trait governed mainly by the immune system and its interactions with many physiologic and environmental factors.
Gruys, E. +5 more
core +2 more sources
Genome-wide analysis reveals the extent of EAV-HP integration in domestic chicken [PDF]
Background: EAV-HP is an ancient retrovirus pre-dating Gallus speciation, which continues to circulate in modern chicken populations, and led to the emergence of avian leukosis virus subgroup J causing significant economic losses to the poultry industry.
A Fumihito +65 more
core +6 more sources
Abstract Both, jawless and jawed vertebrates possess three lymphocyte lineages defined by highly diverse antigen receptors: Two T‐cell‐ and one B‐cell‐like lineage. In both phylogenetic groups, the theoretically possible number of individual antigen receptor specificities can even outnumber that of lymphocytes of a whole organism.
Thomas Herrmann +2 more
wiley +1 more source
A metagenomic comparison of endemic viruses from broiler chickens with runting stunting syndrome and from normal birds [PDF]
Runting-stunting syndrome (RSS) in broiler chickens is an enteric disease that causes significant economic losses to poultry producers worldwide due to elevated feed conversion ratios, decreased body weight during growth, and excessive culling.
Devaney, Ryan +4 more
core +1 more source
This study analyses the evolutionary trajectory of a novel virus over its 17‐year history, examining the dynamics of its host relationships and its patterns across geographic space and evolutionary time. We sequence its entire genome and discern that the virus has significantly changed, with its original genotypes disappearing and being replaced in a ...
Carol A. Stepien, Megan D. Niner
wiley +1 more source
Seroprevalence of avian leukosis virus in local chickens in five live bird markets, Kaduna metropolis, North-western Nigeria [PDF]
Avian leukosis virus is recognized as an important viral pathogen in the poultry industry, resulting in salient severe economic losses due to reduced production, uneven flock growth rates, reduced growth, and immunosuppression which predispose affected ...
Bakam, J.D. +5 more
core +2 more sources

