Results 71 to 80 of about 12,002,276 (313)

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Does integrated science education improve scientific literacy?

open access: yesJETEN, 2014
In Flanders, a choice has been made for the integrated school subject ‘Natural Sciences’, in ‘science for all’ secondary school trajectories, and for the three separate subjects biology, physics and chemistry, in trajectories for the future scientist and
Laura Tamassia, Renaat Frans
doaj  

Subject metadata support powered by Maui [PDF]

open access: yes, 2010
Selecting subject headings and keywords is a chore for all metadata editors, who often leave these fields blank or incomplete—even when there are no guidelines and any word or phrase can be chosen.
Medelyan, Olena   +2 more
core   +2 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Index Subject

open access: yesHumaniora, 2017
Index Subject
doaj   +3 more sources

Effect of sowing time on productivity and economics of okra (Abelmoschus esculentus) under semi-arid conditions

open access: yesThe Indian Journal of Agricultural Sciences, 2015
An investigation to study the effect date of sowing on productivity of okra (Abelmoschus esculentus L. Moench) cv. Gujarat Okra 2 was carried out at the five farmer's field at Panchmahals district of central Gujarat under on farm trial during 2011-12 ...
RAJ KUMAR   +4 more
doaj   +1 more source

References: (a) DoD Directive 5110.4, “Washington Headquarters Services (WHS),” [PDF]

open access: yes
reissues Reference (b) to disseminate policies and update responsibilities and procedures for selection of employees covered by merit promotion. 2. APPLICABILITY. See Enclosure 1. 3. POLICY. It is OSD policy that: a.
Subject Merit Promotion
core  

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Jesus and the six objectives of Daniel 9:24

open access: yesIn die Skriflig, 2015
Although Daniel 9:24–27 addresses the Antiochene crisis of the second century bce, many of Jesus’ followers have read this passage with reference to his first and second comings.
Dean R. Ulrich
doaj   +1 more source

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