Results 91 to 100 of about 1,882,325 (309)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Aerospace medicine and biology: A continuing bibliography with indexes (supplement 359) [PDF]

open access: yes
This bibliography lists 164 reports, articles and other documents introduced into the NASA Scientific and Technical Information System during Jan. 1992.

core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

ASEAN and the non-traditional regional security agenda [PDF]

open access: yes, 2010
Without a doubt, the whole area of non-traditional security – whether it be threats, issues or challenges (the three are more or less used interchangeably in ASEAN statements and documents on the subject) – has come to occupy a prominent place on the ...
Rolls, Mark G.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

La muerte en Sahagún a partir del registro notarial de Sancho de Escobar (1486)

open access: yesE-Spania
Notarial Registers are an extraordinary source for the study of medieval society in all its manifestations, one of which is death. Several studies have already been carried out on this subject, based on the documents contained in these diplomatics ...
Guillermo Fernández Ortiz
doaj   +1 more source

Bibliography on aerodynamics of airframe/engine integration of high-speed turbine-powered aircraft, volume 1 [PDF]

open access: yes
This bibliography was developed as a first step in the preparation of a monograph on the subject of the aerodynamics of airframe/engine integration of high speed turbine powered aircraft.
Nichols, M. R.
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Dyplomy ormiańskie w zbiorach Działu Rękopisów Zakładu Narodoweg o im. Ossolińskich

open access: yesLehahayer, 2015
In the Wrocław collections of the Zakład Narodowy im. Ossolińskich [The National Ossoliński Institution] there are 3270 diplomas among which only seventeen may be classified as documents which are associated with Armenians in any way.
Konrad Rzemieniecki
doaj  

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