Results 71 to 80 of about 196,069 (314)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

L'estiueig a Gelida 1880-1940 : anàlisi dels fons documentals i fotogràfics [PDF]

open access: yes, 2015
El treball pretén elaborar un estat de la qüestió sobre el fenomen de l'estiueig a Gelida entre les dècades de 1880 a 1940, des d'una vessant arxivística.
Universitat Autònoma de Barcelona. Escola Superior d'Arxivística i Gestió de Documents   +1 more
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Categorization Schemes in Web of Science CC

open access: yesInformaciâ i Innovacii, 2018
The article presents the analysis of the two classification schemes that are integrated in Web of Science Core Collection - the “Web of Science Categories” and “Research Areas”.
Yu. V. Mokhnacheva
doaj   +1 more source

Classification of Keywords Extracted from Research Articles Published in Science Journals [PDF]

open access: yes, 2008
This paper is based on an analytical study of 335 keywords extracted from titles and abstracts of 70 research articles, taking ten from each year starting from 2000 to 2006, in decreasing order of relevance, on the subject Fermi Liquid, which is a ...
Sen, B. K.   +3 more
core  

Performances of Online Public Access Catalogues in Retrieval of Bengali Documents by Subject [PDF]

open access: yes, 2014
Study investigates the performances of Online Public Access Catalogues (OPACs) in retrieval of Bengali documents by subject. Traces general search functionalities, subject retrieval, subject display in the bibliographic record, merits and demerits of the
Halder, Sambhu Nath   +2 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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