Results 111 to 120 of about 120,098 (307)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Documents of the Coronado Expedition, 1539-1542: "They Were Not Familiar with His Majesty, nor did They Wish to be His Subjects" (review) [PDF]
, 2006 Jean A. Stuntz
openalex +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
An Inquiry into the Origin and Nature of the Yellow Fever, as it Has Lately Appeared in the West Indies, with Official Documents Relating to This Subject [PDF]
W. N. Fergusson
openalex +1 more source
Eyeing the Pedagogy of Trouble: The Cultural Documentation of the Problem-Subject
Canadian Journal of Disability Studies, 2017 Blindness lives in a world, one both organized and defined by the eye that sees itself as sighted. Seeing is believing, and this belief, eyes believe, is learning. But, what if the eyes that are “seeing” are “blind”? Do we believe these eyes as we do those that see? Do we learn from blind eyes as we do from sighted ones?This paper seeks to question not
openaire +2 more sources
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source