Results 71 to 80 of about 120,098 (307)
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
International Journal of Information Science and Management, 2012 The purpose of this paper was to study and map the intellectual structure of Iranian physicists using author co-citation technique during 1990-2009.
F. Osareh, R. Khademi
doaj
Towards an Estonian dataset on document-level subjectivity
Eesti ja soome-ugri keeleteaduse ajakiri. Journal of Estonian and Finno-Ugric LinguisticsThis article discusses a preparatory step towards developing an Estonian dataset on subjectivity, providing a brief overview of past analyses of subjectivity and the theoretical basis for creating the dataset. Subjectivity has been explored within many fields of linguistics, including pragmatics and formal semantics, as well as natural language ...
Karl Gustav Gailit +2 more
openaire +2 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Categorization Schemes in Web of Science CC
Informaciâ i Innovacii, 2018 The article presents the analysis of the two classification schemes that are integrated in Web of Science Core Collection - the “Web of Science Categories” and “Research Areas”.
Yu. V. Mokhnacheva
doaj +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
The Institution of Slavery in Ancient Anatolia in the Light of New Documents
Belleten, 1996 The oldest written documents of Anatolia, the so-called Kültepe tablets, which at present number more than 20.000, mostly deal with commercial subjects.
Sebahattin Bayram, Salih Çeçen
doaj +1 more source