Results 51 to 60 of about 73,106 (263)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
ЭЛЕКТРОННЫЙ МЕТОДИЧЕСКИЙ АППАРАТ ПРЕДМЕТИЗАТОРА В ГПНТБ СО РАН
The formation of rules and methodical instrument for a subject cataloger began in SPSTL SB RAS in 2007. The authors describe the structure, functions and technology of operating the electronic file of methodical decisions on subject cataloging.
doaj
The University of Kansas has hosted the Kansas Working Papers in Linguistic (KWPL) in its digital repository, KU ScholarWorks, since 2007, but complete subject metadata, based on Library of Congress Subject Headings, was added only in 2013.
Husic, Geoff
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Subject headings lists ahd thesaurus initiatives for equity and social justice.
The research aimed to describe initiatives for creating and updating subject heading lists and thesaurus considering social justice and equity, based on the literature from the sociocultural dimension of Knowledge Organization.
Fabíola Rubim Silva +1 more
doaj +1 more source
Se analizaron en la Lista de encabezamientos de materia para biblioteca (LEMB) los epígrafes referidos a raza, según criterios de otredad, confinamiento, omisión, estructura inadecuada y terminología tendenciosa.
Alicia J. Todaro, Ana M. Martínez
doaj +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Blind links, a big challenge in the linked data idea: Analysis of Persian Subject Headings
In this survey, Linked data concept as exposing, sharing, and connecting pieces of data, information, and knowledge on the Semantic Web and some potential problems in converting Persian subject headings (PSHs) Records into linked data were discussed.
Atefeh Sharif
doaj
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source

