Results 61 to 70 of about 5,606,045 (335)

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Predicting Basic Concepts of a Field, Based on the Factors of Oldness and Frequency Use of Subject Terms: A Case Study on Colon Cancer

مدیریت اطلاعات سلامت, 2016
Introduction: Prediction of future subjects is a necessity for policy making in science field, which is done by different variables. Accordingly, present research was conducted to predict basic concepts in the field of colon cancer based on the factor of
Mojtaba Mokhtari-Shamsi, Mohammad Tavakolizadeh-Ravari, Ebrahim Zalzadeh, Mahmoud Baghbanian   +3 more
doaj  

Categorization of postoperative pain descriptors in the sensitive, affective and evaluative dimensions of painful experiences Categorización de los descriptores del dolor postoperatorio en las dimensiones sensorial, afectiva y evaluadora de esa experiencia Categorização de descritores da dor pós-operatória nas dimensões sensitiva, afetiva e avaliativa da experiência dolorosa

Revista Latino-Americana de Enfermagem, 2007
The main purpose of this study was categorizing 20 descriptors of post-operative pain sensory, affective and evaluative dimensions. Sixty-one physicians participated.
Lilian Varanda Pereira, Fátima Aparecida Emm Faleiros Sousa   +1 more
doaj   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Leveraging a Custom Python Script to Scrape Subject Headings for Journals

Code4Lib Journal, 2021
In our current library fiscal climate with yearly inflationary cost increases of 2-6+% for many journals and journal package subscriptions, it is imperative that libraries strive to make our budgets go further to expand our suite of resources.
Shelly R. McDavid, Eric McDavid, Neil E. Das   +2 more
doaj  

Subject description of non-fiction literature for adults: expert-theoretical basis for the realisation of the »Hidden Treasure« research project

Knjižnica, 2004
Library users searching through non-fiction library material by subject in online OPACs, expect to be able to search fiction by subject as well. The research project Skriti zaklad (Hidden Treasure) was launched in 2002 and was aimed at improving the ...
Andrej Pogorelec, Alenka Šauperl, Milojka Miklavčič, Darja Šesek, Savina Zwitter   +4 more
doaj   +1 more source

Subject heading 2021

Лечащий Врач, 2022
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openaire   +2 more sources

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Sears List of Subject Headings: An introduction to the Nineteenth Edition (2007)

Pakistan Journal of Information Management & Libraries, 2016
The paper discusses the importance of Vocabulary Control in Subject cataloguing. It gives a brief history of the Sears list from 1923 to 2007, highlights the major changes in all its 19 editions and makes a critical study of the 19th (2007) edition of ...
M. P. Satija
doaj   +1 more source