Results 61 to 70 of about 74,283 (253)

White matter and its relationship with cognition in subjective cognitive decline [PDF]

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2018
Abstract Introduction Subjective cognitive decline (SCD) is the earliest stage on the continuum toward Alzheimer's disease. This study examined (1) differences in white matter integrity between individuals with SCD and healthy control subjects and (2) how white matter integrity related to ...
Lisa Ohlhauser, Ashleigh F. Parker, Colette M. Smart, Jodie R. Gawryluk, Alzheimer's Disease Neuroimaging Initiative   +4 more
openaire   +3 more sources

Machine Learning‐Enhanced Ultrasensitive Immuno‐CRISPR Array Facilitates Early Diagnosis of Alzheimer's Disease by Detecting Multiple Plasma Biomarkers

Advanced Science, EarlyView.
This work presents a CRISPR‐based, ultrasensitive multiplex protein detection array capable of simultaneously analyzing six plasma biomarkers associated with Alzheimer's disease (AD). By integrating antibody‐mediated signal transduction, recombinase polymerase amplification, and spatially encoded CRISPR‐Cas12a, the system achieves detection sensitivity
Liding Zhang, Changwen Yang, Qian Yao, Xuewei Du, Shuai Ding, Yaoqiang Shi, Can Sheng, Ming Wang, Ying Han, Haiming Luo   +9 more
wiley   +1 more source

Association of Neurogranin and BACE1 With Clinical Cognitive Decline in Individuals With Subjective Cognitive Decline

Neurology
CSF biomarkers have immense diagnostic and prognostic potential for Alzheimer disease (AD). However, AD is still diagnosed relatively late in the disease process, sometimes even years after the initial manifestation of cognitive symptoms. Thus, further identification of biomarkers is required to detect related pathology in the preclinical stage and ...
Xiao Wang, Silka D. Freiesleben, Luisa-Sophie Schneider, Lukas Preis, Josef Priller, Eike J. Spruth, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Niels Hansen, Frank Jessen, Ayda Rostamzadeh, Emrah Duzel, Wenzel Glanz, Enise I. Incesoy, Katharina Buerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris-Stephan Rauchmann, Stefan J. Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H.J. Munk, Annika Spottke, Nina Roy-Kluth, Michael T. Heneka, Frederic Brosseron, Michael Wagner, Steffen Wolfsgruber, Alfredo Ramirez, Luca Kleineidam, Melina Stark, Oliver Peters   +35 more
openaire   +6 more sources

Disentangling the relationship of subjective cognitive decline and depressive symptoms in the development of cognitive decline and dementia

Alzheimer's & Dementia, 2022
AbstractIntroductionSubjective cognitive decline (SCD) and depressive symptoms (DS) frequently co‐occur prior to dementia. However, the temporal sequence of their emergence and their combined prognostic value for cognitive decline and dementia is unclear.MethodsTemporal relationships of SCD, DS and memory decline were examined by latent difference ...
Kleineidam, Luca, Wagner, Michael, Luppa, Melanie, Röhr, Susanne, Pentzek, Michael, Wiese, Birgitt, Maier, Wolfgang, Scherer, Martin, Kornhuber, Johannes, Peters, Oliver, Frölich, Lutz, Wiltfang, Jens, Guski, Jannis, Lewczuk, Piotr, Hüll, Michael, Ramirez, Alfredo, Jessen, Frank, Riedel-Heller, Steffi G, Heser, Kathrin, Wolfsgruber, Steffen, Miebach, Lisa, Bickel, Horst, König, Hans-Helmut, Weyerer, Siegfried, Lühmann, Dagmar, Kaduszkiewicz, Hanna   +25 more
openaire   +6 more sources

How Video‐Based Information Affects Farmers' Willingness to Pay for Drone Services

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Professional service for digital technology like agricultural drones lowers transaction costs and scope thresholds for smallholders. Meanwhile, perceptual adoption barriers remain underexplored. We conduct a two‐stage choice experiment with a randomized video‐based information treatment among 384 Chinese crop farmers to measure its effect on ...
Hua Zhang, Lena Kuhn, Hang Xiong, Zhanli Sun, Thomas Glauben   +4 more
wiley   +1 more source

Examining the Role of Aging Perceptions in Subjective Cognitive Decline

Alzheimer Disease & Associated Disorders, 2022
Objective: While subjective cognitive decline (SCD) is gaining ground as a “preclinical” risk state for Alzheimer disease, its utility depends on our understanding of the factors linked to SCD. Rarely examined sociocultural factors including perceptions of aging may relate to the subjective experience of cognitive aging ...
Chapman, Silvia, Weiss, David, Broulíková, Hana M., Sunderaraman, Preeti, Barker, Megan S., Joyce, Jillian L., Azar, Martina, McKeague, Ian, Kriesl, William C., Cosentino, Stephanie   +9 more
openaire   +4 more sources

Promoting Healthier Drinking: Evidence From a Vignette Experiment on Contextual and Informational Drivers of Dealcoholized Wine Choices

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Growing demand for healthier beverages is driving innovation in the wine sector, with dealcoholized wine emerging as a promising alternative. However, little is known about the contextual conditions under which consumers would choose dealcoholized wine, particularly in countries with strong wine traditions. To fill this gap, this work examines
Giovanna Piracci, Giulia Maesano, Leonardo Casini, Maurizio Canavari, Marija Cerjak   +4 more
wiley   +1 more source

Defining Frailty in Chinese‐Language Biomedical Literature (2014–2024): A Decade of Conceptual Evolution

AGING MEDICINE, EarlyView.
Frailty definitions in Chinese‐language biomedical literature increasingly align with international frameworks, while retaining conceptual diversity, underscoring the need for multidimensional, cross‐cultural research and integration with traditional Chinese medicine for culturally sensitive clinical practice.
Haodong Wei, David Mockler, Giulia Cavrini, Nathan W. Hill, Daniel Kam Yin Chan, Román Romero Ortuño   +5 more
wiley   +1 more source

Too Complex to Choose? The Role of Heuristics in Shaping Farmers' Willingness to Pay for Income Stabilization Tool in Italy

Agribusiness, EarlyView.
ABSTRACT European agriculture is increasingly exposed to economic instability driven by extreme weather events, market volatility, and geopolitical tensions. To manage these growing risks, farmers are encouraged to adopt innovative risk management strategies such as the Income Stabilization Tool (IST), which offers protection against severe income ...
Alice Stiletto, Ruggiero Rippo, Samuele Trestini, Elisa Giampietri, Roberta Raffaelli, Simone Cerroni   +5 more
wiley   +1 more source

Is There a Market for Organic Milk in Serbia? Insights From Integrated Choice and Latent Variable Model

Agribusiness, EarlyView.
ABSTRACT Past growth in the global organic market has been concentrated in high‐income countries, while in middle‐income countries such as Serbia the organic market remains nascent and characterized by a sparse assortment of organic products, high retail premia and limited evidence on consumer preferences and their drivers.
Milan Tatic, Sanja Dzever, Bojan Matkovski, Danilo Djokic   +3 more
wiley   +1 more source