Results 41 to 50 of about 74,283 (253)

ExoBDNF Probiotic Supplementation Enhances Cognition in Subjective Cognitive Decline. [PDF]

Medicina (Kaunas)
Background and Objectives: Interventions targeting the gut–brain axis offer potential for mitigating Subjective Cognitive Decline (SCD), a critical window for Alzheimer’s prevention. This study evaluated the effects of a novel probiotic supplement, ExoBDNF, on cognitive function, sleep, and emotional distress in adults with SCD.
Lin CE, Chen LF, Fang WH, Chang CC, Chang HA.   +4 more
europepmc   +3 more sources

Subjective cognitive decline: Self and informant comparisons [PDF]

Alzheimer's & Dementia, 2013
AbstractBackgroundIt is unclear whether self‐ or informant‐based subjective cognition better distinguishes emotional factors from early‐stage Alzheimer's disease (AD).MethodsHealthy members (n = 447) of the Arizona apolipoprotein E (APOE) cohort and their informants completed the self and informant paired Multidimensional Assessment of ...
Richard J, Caselli, Kewei, Chen, Dona E C, Locke, Wendy, Lee, Auttawut, Roontiva, Dan, Bandy, Adam S, Fleisher, Eric M, Reiman   +7 more
openaire   +2 more sources

Cognitive Differences in Subjective Cognitive Decline with and without Associated Worry

Maedica - A Journal of Clinical Medicine, 2022
Objectives:Subjective cognitive decline (SCD) is a heterogenous concept that has been associated with future objective cognitive decline. Our objective was to assess the cognitive function of three groups: one with SCD who claimed to be worried about their symptoms, one with SCD who did not claim to be worried about their symptoms and one without SCD ...
Alexandru, Pavel, Radu, Paun, Maria, Mihalcea, Irina, Dutu, Catalina, Tudose   +4 more
openaire   +2 more sources

Subjective cognitive decline: The first clinical manifestation of Alzheimer's disease?

Dementia & Neuropsychologia
Background: Mild cognitive impairment is considered as the first clinical manifestation of Alzheimer's disease (AD), when the individual exhibits below performance on standardized neuropsychological tests.
Adalberto Studart Neto, Ricardo Nitrini
doaj   +1 more source

Symptom profiles and their influencing factors among people with subjective cognitive decline: a secondary analysis of cross-sectional data from the 2019 Korea Community Health Survey using latent class analysis

BMJ Open, 2023
Objective Subjective cognitive decline, self-perceived cognitive deterioration without objective impairment, is becoming a vital health indicator, especially due to its intermediate stage between normal function and mild cognitive impairment.
Hohyun Seong, Jongmin Park
doaj   +1 more source

The Effect of Hearing Loss on Cognitive Function in Subjective Cognitive Decline

Dementia and Geriatric Cognitive Disorders, 2022
<b><i>Introduction:</i></b> Subjective cognitive decline (SCD) is a self-reported cognitive decline without objective cognitive impairment. The relationship between audiometric hearing loss (HL) and cognitive function has not been reported in SCD.
So Young Park, Seong Hee Ho, Yun Jeong Hong, Jee Hyang Jeong, Kee Hyung Park, SangYun Kim, Min Jeong Wang, Seong Hye Choi, Regina E.Y. Kim, Dong Won Yang, Shi Nae Park   +10 more
openaire   +2 more sources

Impact of subjective cognitive decline on frailty in elderly patients with metabolic syndrome: the parallel mediating effects of physical activity and depression

陆军军医大学学报
Objective Elderly patients with metabolic syndrome often present with concurrent subjective cognitive decline and frailty, yet the underlying mechanisms linking these conditions remain unclear.
WU Nuoy, XU Yuanchun
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

Dementia Incidence in Individuals With Parkinson's Disease in the Framingham Heart Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Limited information exists on incident dementia in individuals with Parkinson's disease (PD) in US community‐based samples. We examined cognitive statuses and PD diagnoses of 183 individuals in the Framingham Heart Study (FHS) to establish incident dementia, mortality rates, associations with sex, age at PD onset, and education level.
Joshi Dookhy, Michael Cummings, Eden Price, Yulin Liu, Santiago Gutierrez‐Gomez, Sarah O'Shea, Samuel Frank, Rhoda Au, Ashita S. Gurnani, Ting Fang Alvin Ang, Jesse Mez, Ludy C. Shih   +11 more
wiley   +1 more source