Results 91 to 100 of about 276,260 (291)

Early Risk Assessment and Recognition of Allergies in Children: Rationale, Methodology, and Proposed Algorithms

Allergy, EarlyView.
ABSTRACT Background Atopic diseases—including atopic dermatitis (AD), food allergy (FA), allergic rhinitis (AR), and asthma—are the most common chronic conditions in childhood and adolescence, affecting up to 30% of the global population. In Germany alone, more than 2.1 million children and adolescents are affected.
E. Hamelmann, B. Schaub, K. Beyer, K. Blümchen, M. Gerstlauer, M. V. Kopp, L. Lange, S. Lau, N. Maison, H. Ott, S. M. Schmidt, T. Spindler, C. Traidl‐Hoffmann, C. Vogelberg   +13 more
wiley   +1 more source

Specific allergen immunotherapy for the treatment of atopic eczema. [PDF]

, 2015
BACKGROUND: Specific allergen immunotherapy (SIT) is a treatment that may improve disease severity in people with atopic eczema (AE) by inducing immune tolerance to the relevant allergen.
Boyle, RJ, Calderon, MA, Durham, S, García Núñez, I, Manikam, L, Nankervis, H, Tam, H, Williams, HC   +7 more
core   +2 more sources

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

Allergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm, Mohammed Zghaebi, Bita Hambrecht, Tanja Kalic, Christopher C. Udoye, Rudolf Manz, Barbara Bohle, Katarzyna M. Sitnik, Julia Eckl‐Dorna, Heimo Breiteneder   +9 more
wiley   +1 more source

Essential role of submandibular lymph node dendritic cells in protective sublingual immunotherapy against murine allergy

Communications Biology, 2020
While sublingual immunotherapy (SLIT) is known as an allergen-specific treatment for type-1 allergies, how it controls allergic pathogenesis remains unclear. Here, we show the prerequisite role of conventional dendritic cells in submandibular lymph nodes
Noriaki Miyanaga, H. Takagi, T. Uto, T. Fukaya, Junta Nasu, Takehito Fukui, Yotaro Nishikawa, T. Sparwasser, N. Choijookhuu, Y. Hishikawa, Takeshi Nakamura, T. Tono, Katsuaki Sato   +12 more
semanticscholar   +1 more source

Comorbid Chronic Rhinosinusitis and Asthma: Shared Risk Factors and Treatment Implications—An EAACI Task Force Report

Allergy, EarlyView.
ABSTRACT Chronic rhinosinusitis (CRS) and asthma are prevalent conditions that often coexist. These diseases share common inflammatory mechanisms, such as T‐helper cell 2 (T2)‐high inflammation, driven by interleukin (IL)‐4, IL‐5, and IL‐13 cytokines.
Sanna Toppila‐Salmi, Sietze Reitsma, Valérie Hox, Simon Gane, Philippe Gevaert, Juan Maza‐Solano, Alma Helevä, Ida Sulku, Kaisa Santala, Iiris Kangasniemi, Ludger Klimek, Adam Chaker, Aspasia Karavelia, Michael Rudenko, Oliver Pfaar, Laura Van Gerven, Shaari Ariana, Michele Schiappoli, Marie Lundberg, Jan Hagemann, Ibon Eguíluz‐Gracia, Andre Moreira   +21 more
wiley   +1 more source

Long-term sublingual bacterial immunotherapy prevents ear, nose and throat infections: A real-life study

SAGE Open Medicine
Objective: Bacterial extracts have been used for many years to prevent airway infections. Recent findings suggest that immunity can be trained by inducing an immunological memory in both the innate and acquired immune response.
Paula F Aarestrup, Matheus F Aarestrup, Beatriz JV Aarestrup, Edir P Cheloni, Fernando M Aarestrup   +4 more
doaj   +1 more source

Use of Sublingual Immunotherapy for Aeroallergens in Children with Asthma

Journal of Clinical Medicine, 2020
Asthma is a heterogeneous disease that in children is often allergen-driven with a type 2 inflammation. Sublingual immunotherapy represents an important progress in the use of personalized medicine in children with allergic asthma.
C. Caffarelli, C. Mastrorilli, Michela Procaccianti, Angelica Santoro   +3 more
semanticscholar   +1 more source

Stepwise approach towards adoption of allergen immunotherapy for allergic rhinitis and asthma patients in daily practice in Belgium : a BelSACI-Abeforcal-EUFOREA statement [PDF]

, 2019
Allergic rhinitis (AR) affects 23-30% of the European population with equal prevalence reported in Belgium. Despite guidelines on the correct use of effective treatment, up to 40% of AR patients remain uncontrolled.
Bachert, Claus, Bousquet, J, Breynaert, C, Bullens, DM, Ceuppens, JL, Clement, G, Cox, T, Ebo, D, Gevaert, Philippe, Halewyck, S, Hellings, PW, Hox, V, Jacobs, R, Ladha, K, Mariën, G, Pugin, B, Rombaux, P, Schrijvers, R, Seys, SF, Speleman, K, Van der Brempt, X, Van Gerven, L, Vanderveken, O, Verhaeghe, B, Vierstraete, K, Vlaminck, S, Watelet, J-B   +26 more
core   +2 more sources

Current Insights Into Individualized Diagnosis and Treatment of Allergic Rhinitis Based on Phenotype and Endotype

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 1, Page 124-135, February 2026.
ABSTRACT Allergic rhinitis (AR) is a chronic inflammatory disease of the nasal mucosa characterized by allergen sensitization and the involvement of multiple inflammatory mediators. Currently, the treatment of AR mainly includes symptomatic relief, anti‐inflammatory therapy, and nerve desensitization. However, these treatments have limitations in fully
Yue Gu, Long‐Lan Shu, Tao Lu, Da‐Yu Guan, Bo‐Wen Zheng, Pan‐Hui Xiong, Yang Shen, Yu‐Cheng Yang   +7 more
wiley   +1 more source

No Severe Anaphylaxis in Clinical Trials of House Dust Mite Sublingual Immunotherapy Tablet Using a Standardized Identification Algorithm [PDF]

, 2021
Veronica Hulstroem, Ruta Gronskyte Juhl, Hendrik Nolte   +2 more
openalex   +1 more source