Results 71 to 80 of about 10,579 (231)

How safe are the biologicals in treating asthma and rhinitis? [PDF]

, 2009
A number of biological agents are available or being investigated for the treatment of asthma and rhinitis. The safety profiles of these biologic agents, which may modify allergic and immunological diseases, are still being elucidated.
Linda S Cox, ED Bateman, R Naclerio, TW Guilbert, T Bongartz, L Carmona, FE Simons, AFC Gonzalez-Perez, HA Sampson, WJ Pichler, DW MacGlashan Jr, H Lin, C Prussin, H Lin, T Nagakura, TB Casale, H Milgrom, W Busse, Expert Panel Report 3 (EPR-3), M Humbert, D Aaronson, SL Limb, L Cox, FDA, AA Cruz, L Jacobsen, SR Durham, A Des Roches, SJ Till, SR Durham, GE Stewart 2nd, DG Tinkelman, L Cox, AI Tabar, MJ Reid, RF Lockey, DI Bernstein, HS Amin, B Bohle, LS Cox, EH Dunsky, AO Eifan, A Antico, L Blazowski, MM Cochard, H Groot, TB Casale, PS Creticos, DI Bernstein, KJ Drachenberg, KJ Drachenburg, N Mothes, KJ Drachenberg, KJ Drachenberg, TK Hart, P Flood-Page, JK Garrett, ML Stein, S Wenzel, MA Berry, SE Wenzel, JC Davis Jr, V Gerloni, JP Leombruno, FDA, C Botsios, D Furst, E Toussirot, GA Settipane   +68 more
core   +1 more source

Autoclaved Peanuts Exhibit Reduced Immunoglobulin E Binding and Improved Oral Tolerability

Allergy, EarlyView.
This study evaluates the effects of heat and pressure autoclaving on peanut proteins, IgE binding, and oral tolerability. Heat and pressure autoclaving breaks down peanut proteins and allergens, contributing to reduced peanut‐specific IgE binding. Autoclaved peanuts are associated with decreased skin test reactivity and greater oral tolerability in ...
Casey G. Cohen, Diana Toscano‐Rivero, Eisha A. Ahmed, Adnan Al Ali, Wei Zhao, Danbing Ke, Duncan Lejtenyi, Liane Beaudette, Hana Chazbey, Abdulaziz S. Alrafiaah, Carmen H. Li, Kurt Dejgaard, Albert M. Berghuis, Bertrand J. Jean‐Claude, Christine McCusker, Thomas Eiwegger, Moshe Ben‐Shoshan, Bruce D. Mazer   +17 more
wiley   +1 more source

Impact of sublingual immunotherapy on seasonal asthma and skin reactivity in children allergic to Parietaria pollen treated with inhaled fluticasone propionate [PDF]

, 2003
Immunotherapy is a recognized treatment for allergic respiratory ...
Barberio, G., Caminiti, L, LA GRUTTA, Stefania, Pajno, G, Parmiani, S, Vita, D   +5 more
core   +1 more source

Long-term sublingual bacterial immunotherapy prevents ear, nose and throat infections: A real-life study

SAGE Open Medicine
Objective: Bacterial extracts have been used for many years to prevent airway infections. Recent findings suggest that immunity can be trained by inducing an immunological memory in both the innate and acquired immune response.
Paula F Aarestrup, Matheus F Aarestrup, Beatriz JV Aarestrup, Edir P Cheloni, Fernando M Aarestrup   +4 more
doaj   +1 more source

Early Risk Assessment and Recognition of Allergies in Children: Rationale, Methodology, and Proposed Algorithms

Allergy, EarlyView.
ABSTRACT Background Atopic diseases—including atopic dermatitis (AD), food allergy (FA), allergic rhinitis (AR), and asthma—are the most common chronic conditions in childhood and adolescence, affecting up to 30% of the global population. In Germany alone, more than 2.1 million children and adolescents are affected.
E. Hamelmann, B. Schaub, K. Beyer, K. Blümchen, M. Gerstlauer, M. V. Kopp, L. Lange, S. Lau, N. Maison, H. Ott, S. M. Schmidt, T. Spindler, C. Traidl‐Hoffmann, C. Vogelberg   +13 more
wiley   +1 more source

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

Allergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm, Mohammed Zghaebi, Bita Hambrecht, Tanja Kalic, Christopher C. Udoye, Rudolf Manz, Barbara Bohle, Katarzyna M. Sitnik, Julia Eckl‐Dorna, Heimo Breiteneder   +9 more
wiley   +1 more source

Effect of Pollen-Specific Sublingual Immunotherapy on Oral Allergy Syndrome [PDF]

, 2008
BACKGROUND: Oral allergy syndrome (OAS) triggered by fruit and vegetables often occurs in patients with pollen-induced rhinoconjunctivitis because of cross-reactive epitopes in pollen and associated foods.
Hendrik Wolf, Jörg Schnitker, Karl-Christian Bergmann   +2 more
core   +1 more source

Comorbid Chronic Rhinosinusitis and Asthma: Shared Risk Factors and Treatment Implications—An EAACI Task Force Report

Allergy, EarlyView.
ABSTRACT Chronic rhinosinusitis (CRS) and asthma are prevalent conditions that often coexist. These diseases share common inflammatory mechanisms, such as T‐helper cell 2 (T2)‐high inflammation, driven by interleukin (IL)‐4, IL‐5, and IL‐13 cytokines.
Sanna Toppila‐Salmi, Sietze Reitsma, Valérie Hox, Simon Gane, Philippe Gevaert, Juan Maza‐Solano, Alma Helevä, Ida Sulku, Kaisa Santala, Iiris Kangasniemi, Ludger Klimek, Adam Chaker, Aspasia Karavelia, Michael Rudenko, Oliver Pfaar, Laura Van Gerven, Shaari Ariana, Michele Schiappoli, Marie Lundberg, Jan Hagemann, Ibon Eguíluz‐Gracia, Andre Moreira   +21 more
wiley   +1 more source

Safety and feasibility of oral immunotherapy to multiple allergens for food allergy [PDF]

, 2014
BACKGROUND: Thirty percent of children with food allergy are allergic to more than one food. Previous studies on oral immunotherapy (OIT) for food allergy have focused on the administration of a single allergen at the time. This study aimed at evaluating
Alanna Blakemore, Anjuli Mehrotra, Anthony Trela, Bethany Kausch, Elisabeth Hoyte, Gerri O’Riordan, Kari C Nadeau, Liane Bacal, Lisa C Winterroth, Margie Woch, Philippe Bégin, Robert G Hamilton, Scott Seki, Shruti P Wilson, Tina Dominguez   +14 more
core   +1 more source

The efficacy of sublingual immunotherapy for allergic diseases in Asia

Allergology International, 2018
Sublingual immunotherapy (SLIT) has been proven to be safe and effective from an abundance of Western literature, but data from Asia is less complete. This review aims to examine the basic science, safety and efficacy of SLIT in Asian patients, and to ...
Xuandao Liu, Chew Lip Ng, De Yun Wang
doaj   +1 more source