Results 91 to 100 of about 671,072 (327)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Understanding Health Risks for Adolescents in Protective Custody [PDF]

open access: yes, 2019
Children in child welfare protective custody (e.g., foster care) are known to have increased health concerns compared to children not in protective custody. The poor health documented for children in protective custody persists well into adulthood; young
Beal, Sarah J.   +3 more
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Caffeine consumption of medical students in Korea: amount and symptoms based on a 2023 survey [PDF]

open access: yesKorean Journal of Medical Education
Purpose To investigate the form and level of daily caffeine intake recommended above 400 mg in medical students expected to consume caffeinated beverages to enhance their performance.
Seong Woo Choi   +6 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Prevalence and risk factors for drug use and dependence in university students from Medellín, Colombia, 2009

open access: yesRevista Facultad Nacional de Salud Pública, 2012
Objective: to determine the prevalence and risk factors for druguse and dependence among students at a university in Medellín,Colombia. Methodology: an analytical study in which 1264students were surveyed using a random sampling, stratified bythe number ...
Andrés F. Tirado O   +5 more
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

ASSISTANCE TO ADOLESCENTS WHO USE PSYCHOACTIVE SUBSTANCES: ROLE OF THE PSYCHOSOCIAL CARE CENTER

open access: yesCogitare Enfermagem, 2017
The present study aimed to gain insight into the role of a Psychosocial Care Center for Users of Alcohol and other Drugs (CAPS AD) that assists adolescents who usepsychoactive substances, from the views of the professionals of Guardianship Councils and ...
Bruna Rios Paim   +6 more
doaj   +1 more source

La investigación biomédica sobre abuso de sustancias a través de la base de datos Medline (2006-2010) [PDF]

open access: yes, 2015
El Abuso de sustancias es uno de los principales problemas sociales y de salud pública a escala mundial. Este estudio analiza la investigación científica sobre los trastornos relacionados con sustancias generado a lo largo del período 2006-2010 así como ...
Agulló Calatayud, Víctor   +3 more
core  

A 10-year Study of Factors Associated with Alcohol Treatment Use and Non-use in a U.S. Population Sample [PDF]

open access: yes, 2016
Background This study seeks to identify changes in perceived barriers to alcohol treatment and predictors of treatment use between 1991–92 and 2001–02, to potentially help understand reported reductions in treatment use at this time.
Caetano, Raul   +3 more
core   +2 more sources

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