Results 91 to 100 of about 601,648 (321)
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Event-related functional magnetic resonance imaging of reward-related brain circuitry in children and adolescents [PDF]
, 2007 BACKGROUND: Functional disturbances in reward-related brain systems are thought to play a role in the development of mood, impulse, and substance abuse disorders. Studies in non-human primates have identified brain regions, including the dorsal / ventral
May, John Christopher
core
Revista Facultad Nacional de Salud Pública, 2012 Objective: to determine the prevalence and risk factors for druguse and dependence among students at a university in Medellín,Colombia. Methodology: an analytical study in which 1264students were surveyed using a random sampling, stratified bythe number ...
Andrés F. Tirado O +5 more
doaj
FEBS Open Bio, EarlyView.Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui +15 more
wiley +1 more source
Attention to the people with substance-related disorders at spanish prisons [PDF]
, 2017 Trabajo fin de grado en EnfermeríaIntroducción: El consumo de drogas genera alteraciones a nivel biopsicosocial y puede dar lugar al ingreso en penitenciarías.
Alonso Valero, Irene +1 more
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The relationship of individual comorbid chronic conditions to diabetes care quality. [PDF]
, 2015 ObjectiveMultimorbidity affects 26 million persons with diabetes, and care for comorbid chronic conditions may impact diabetes care quality. The aim of this study was to determine which chronic conditions were related to lack of achievement or ...
Bolt, Daniel M +7 more
core +2 more sources
Frontiers in PharmacologyIntroductionSubstance abuse is a major public health problem. In recent years, ketamine, which is a parenteral anesthetic, has been consumed increasingly as an illicit drug together with alcohol, although little is known of how this association alters ...
Luan Oliveira Ferreira +11 more
doaj +1 more source
ASSISTANCE TO ADOLESCENTS WHO USE PSYCHOACTIVE SUBSTANCES: ROLE OF THE PSYCHOSOCIAL CARE CENTER
Cogitare Enfermagem, 2017 The present study aimed to gain insight into the role of a Psychosocial Care Center for Users of Alcohol and other Drugs (CAPS AD) that assists adolescents who usepsychoactive substances, from the views of the professionals of Guardianship Councils and ...
Bruna Rios Paim +6 more
doaj +1 more source
Medwave, 2018 Resumen Las benzodiacepinas son fármacos ampliamente utilizados en atención primaria de salud. Su uso prolongado se ha convertido en un problema relevante dadas las consecuencias médicas que ocasionan, especialmente en adultos mayores.
Josefina Aguiluz +4 more
doaj +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik +2 more
wiley +1 more source