Results 91 to 100 of about 1,257,231 (376)
Trends In Substance Use And Related Disorders.
Deutsches Ärzteblatt International, 2019 BACKGROUND Changes in the use of psychoactive substances and medications and in the occurrence of substance-related disorders enable assessment of the magni- tude of the anticipated negative consequences for the population. METHODS Trends were analyzed
N. Seitz +5 more
semanticscholar +1 more source
The classification of substance and behavioural addictions: A preliminary investigation [PDF]
, 2012 The term addiction has been used to refer to impaired control over substance use for several centuries however recently there has been a shift toward using this term in the context of non-substance use disorders, such as pathological gambling.
McLaughlan, Andre David +1 more
core +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
A potential biomarker of cognitive impairment: The olfactory dysfunction and its genes expression
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1884-1897, December 2022., 2022 Abstract Objective Accumulation evidence has reported that olfactory impairment may be an essential clinical marker and predictor of mild cognitive impairment or Alzheimer's disease. Method Participants were enrolled in the population‐based, prospective study in Fuxin county, Liaoning province, China between 2019 and 2021.
Jiayi Song +11 more
wiley +1 more source
Contractures and Drug Abuse [PDF]
Indian Journal of Physical Medicine & Rehabilitation, 2009 Contracture is limitation of complete range of motion,active or passive, due to joint, muscle or soft-tissuelimitations. Myogenic contractures can be due to trauma,inflammation, degenerative changes, ischemia, andspasticity.
Srikumar V +4 more
doaj
Childhood maltreatment and amygdala connectivity in methamphetamine dependence: a pilot study. [PDF]
, 2014 IntroductionChildhood maltreatment, a well-known risk factor for the development of substance abuse disorders, is associated with functional and structural abnormalities in the adult brain, particularly in the limbic system.
Dean, Andy C +3 more
core +2 more sources
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Effects of pregnancy on neuromyelitis optica spectrum disorder and predictors of related attacks
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1918-1925, December 2022., 2022 Abstract Objective Our study aimed to investigate the influence of pregnancy on the course of neuromyelitis optica spectrum disorders (NMOSD) and to explore the independent predictors of pregnancy‐related attacks. Methods We performed a retrospective study of patients with NMOSD based on the Wingerchuk 2006 or the revised Wingerchuk 2015 criteria ...
Qin Du +7 more
wiley +1 more source
Interference in disordered systems: A particle in a complex random landscape [PDF]
Phys. Rev. E 83, 061116 (2011), 2011 We consider a particle in one dimension submitted to amplitude and phase disorder. It can be mapped onto the complex Burgers equation, and provides a toy model for problems with interplay of interferences and disorder, such as the NSS model of hopping conductivity in disordered insulators and the Chalker-Coddington model for the (spin) quantum Hall ...
arxiv +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source