A study of high risk behaviour among LGBT people of Manipur
Aim: Over the last two decades, there has been increasing demand for the awareness on sexual minority people’s lives and issues throughout the world. In the recent years, India is witnessing a change in public attitude and concern in the field of sexual ...
Niranjan Hebbar YR, Rajkumar Lenin Singh
doaj +1 more source
Error-related brain activity as a transdiagnostic endophenotype for obsessive-compulsive disorder, anxiety and substance use disorder [PDF]
Background Increased neural error-signals have been observed in obsessive-compulsive disorder (OCD), anxiety disorders, and inconsistently in depression. Reduced neural error-signals have been observed in substance use disorders (SUD). Thus, alterations
Bey, Katharina +8 more
core +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling +4 more
wiley +1 more source
Pattern of psychoactive substance use by students - Ribeirão Preto
The aim was to analyze the use of psychoactive substances among students in their final year of middle school and high school in Ribeirão Preto and reflect on the pattern of psychoactive drug use based on epidemiological studies conducted over the last ...
Margarita Antonia Villar Luis +4 more
doaj +1 more source
Editorial: Impulsivity and compulsivity related to substance use disorders
Francisca López-Torrecillas
doaj +2 more sources
Risk factors for incidence and persistence of disability in chronic major depression and alcohol use disorders: longitudinal analyses of a population-based study [PDF]
BackgroundMajor depression and alcohol use disorders are risk factors for incidence of disability. However, it is still unclear whether a chronic course of these health conditions is also prospectively associated with incidence of disability.
Ayuso-Mateos, J. +4 more
core +1 more source
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Understanding Health Risks for Adolescents in Protective Custody [PDF]
Children in child welfare protective custody (e.g., foster care) are known to have increased health concerns compared to children not in protective custody. The poor health documented for children in protective custody persists well into adulthood; young
Beal, Sarah J. +3 more
core +2 more sources
Racial/ethnic variations in substance-related disorders among adolescents in the United States.
CONTEXT While young racial/ethnic groups are the fastest growing population in the United States, data about substance-related disorders among adolescents of various racial/ethnic backgrounds are lacking. OBJECTIVE To examine the magnitude of past-year
Li-Tzy Wu +4 more
semanticscholar +1 more source

