Results 121 to 130 of about 1,113,798 (313)

Comparative Analysis of Coagulation and Liver Parameters in Individuals with Alcohol and Substance Use Disorders and Healthy Controls

open access: yesDiagnostics
Background/Objectives: Alcohol Use Disorder (AUD) and Substance Use Disorders (SUDs) can affect both the liver, where clotting factors are synthesized, and the coagulation system, which prevents acute bleeding. Methods: This study included 451 inpatients
Şeyma Bardakçı   +4 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Формування предметного поля метафізичних категорій у просторі філософських ідей Пізньої схоластики / The Formation of the Subject Field of Metaphysical Categories in Terms of Philosophical Ideas of Late Scholastic

open access: yesАктуальні питання суспільних наук та історії медицини, 2014
Skrytska Natalya. The Formation of the Subject Field of Metaphysical Categories in Terms of Philosophical Ideas of Late Scholastics. The article considers the nature of such metaphysical concepts as essence, being, God, substance, logical quantifier ...
Скрицька Наталія
doaj  

Addiction Phenomenology In Substance Use And Non-Substance Use Disorders

open access: yes, 2008
There is growing research evidence and public concern over the burgeoning of disorders which share common features with substance addictions. In order to investigate the presence and role of addiction features in disorders outside of substance addictions,
McLachlan, Andre David
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Science in the Courtroom EU Courts Wisely Steer Clear of Judicial Passivism Joined Cases C-71/23 P and C-82/23 P, France and Commission/CWS Powder Coatings and Others [2025] ECLI:EU:C:2025:601

open access: yesEuropean Journal of Risk Regulation
In a ruling delivered on 1 August 2025, the Court of Justice upheld a General Court judgment annulling the classification as a suspected carcinogen of titanium dioxide in powder form containing at least 1% of particles of a diameter equal to or below 10 ...
Antoine Bailleux
doaj   +1 more source

The association between sleep problems, learning disabilities and substance use in adolescence

open access: yes, 2007
Includes bibliographical references (leaves 90-112)The current study focused on investigating the relationship between sleep problems, learning disabilities and substance use in adolescence.
Fakier, Nuraan
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Substance-Related Psychiatric Emergencies

open access: yes, 2016
Substance-Related Psychiatric ...
Adam D Miller (10997982)   +2 more
core  

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

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