Results 101 to 110 of about 1,013,046 (307)
International Journal of Pediatrics, 2011 The multiple risks associated with methamphetamine use are of serious concern for women. These risks and consequences are magnified during pregnancy. This secondary analysis of a parent study compared 26 pregnant to 356 nonpregnant women in Cape Town ...
Hendrée E. Jones +8 more
doaj +1 more source
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
BMC Cardiovascular DisordersBackground Dyslipidemia poses a significant challenge to public health worldwide. Many researchers have suggested that nutritional and environmental factors contribute to dyslipidemia.
Samaneh Nakhaee +4 more
doaj +1 more source
A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau
Advanced Science, EarlyView.TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun +12 more
wiley +1 more source
Advanced Science, EarlyView.Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao +10 more
wiley +1 more source
Therapeutic Community Effectiveness on Self-Esteem and Relapse Rate among Drug Users
Journal of Rehabilitation, 2012 Objective: In recent years, the Therapeutic Community(TC) has become a widespread treatment alternative for drug addicts. TC have been widely studied with emphasis on thair effectiveness.
Mosayyeb Yarmohammadi-Vasel +3 more
doaj
Depression and Substance Abuse: A Rationalization of a Vicious Circle [PDF]
While a mind-altering-substance consumption alleviates current level of depression, it facilitates future depression. Our analysis incorporates this trade off and shows that the stationary state of a consistently overly ambitious sophisticated substance ...
Faria, João Ricardo, Levy, Amnon
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Societal Response to Developmental Differences and Adolescent Substance Abuse Treatment Outcomes [PDF]
, 2002 Recent findings indicate an increased concern that conventional substance abuse treatment models consistently reflect less than satisfactory outcomes when applied to adolescents.
Osborne, Randall R.
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Advanced Science, EarlyView.Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li +17 more
wiley +1 more source
Other title: Substance abuse epidemiological indicators profile
, 2006 Cover title.; Date taken from file name.; "Funded through a grant awarded by the U.S. Department of Health and Human Services, Public Health Service, Substance Abuse and Mental Health Services Administration, Center for Substance Abuse Prevention ...
Kansas. Department of Social and Rehabilitation Services.
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