Results 31 to 40 of about 3,724,758 (302)

Discrimination Between Drug Abuse and Medical Therapy : Case report of a tranylcypromine overdose-related fatality

open access: yesSultan Qaboos University Medical Journal, 2017
Tranylcypromine is an effective antidepressant from the class of monoamine oxidase inhibitors and is structurally related to amphetamine. However, reports differ regarding the potential metabolism of tranylcypromine to amphetamine and methamphetamine ...
Maryam Akhgari   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Substance abuse treatment: what do we know? an economist's perspective [PDF]

open access: yes, 2003
The substance abuse treatment literature has basically dealt with four important questions: 1) Is treatment effective? 2) Are all programs equally effective? 3) why do programs differ in their effectiveness?
Machado, Matilde P.
core   +1 more source

Trends in substance use profiles at Bursa City Hospital pediatric emergency department (2020–2026): A retrospective analysis

open access: yesAddicta: The Turkish Journal on Addictions
This study aimed to retrospectively evaluate urine toxicology screening (UTS) profiles, multi-year substance use trends, and clinical correlation parameters in patients aged 0–18 years who presented to the Pediatric Emergency Department of Bursa City ...
Emre Çelik   +4 more
doaj   +1 more source

Perioperative management of patients with drug addiction

open access: yesМедицина неотложных состояний, 2023
Background. Patients undergoing surgical or diagnostic procedures, as well as critically ill patients, often suffer from psychoactive substance use disorders. The term “psychoactive substances” here includes both narcotics and psychotropic substances (or
Yu.I. Markov
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Social indicators associated with substance abuse

open access: yes, 1997
Cover title.; "Prepared for Connecticut's Department of Mental Health and Addiction Services as part of its Substance Abuse Prevention Needs Assessment, (CSAP Contract #277-95-1037)."; "March 1997."; Accompanied by appendices.; Funded by the U.S.
Stein-Seroussi, Alan.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Sphincter of oddi dysfunction induced by ketamine: A case report

open access: yesClinical Case Reports
Key Clinical Message Chronic ketamine use can lead to sphincter of oddi dysfunction (SOD), causing various hepatobiliary complications. Recognizing substance abuse history is vital for early detection.
Nava Raj Sharma   +6 more
doaj   +1 more source

A formação do enfermeiro e o fenômeno das drogas no Sul do Brasil: atitudes e crenças dos estudantes de enfermagem sobre o cuidado La formación del enfermero y el fenómeno de las drogas en el Sul de Brasil: actitudes y creencias de estudiantes de enfermería sobre la atención Nursing formation and the drugs phenomenon in the South of Brazil: nursing students' attitudes and beliefs on care

open access: yesRevista Latino-Americana de Enfermagem, 2005
Pesquisa descritiva sobre a formação do enfermeiro e sua relação com o fenômeno das drogas, realizada com alunos do último período de Graduação em Enfermagem de cinco Instituições Federais de Ensino Superior do sul do Brasil.
Telma Elisa Carraro   +2 more
doaj   +1 more source

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