Results 31 to 40 of about 48,018 (311)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A formação do enfermeiro e o fenômeno das drogas no Sul do Brasil: atitudes e crenças dos estudantes de enfermagem sobre o cuidado La formación del enfermero y el fenómeno de las drogas en el Sul de Brasil: actitudes y creencias de estudiantes de enfermería sobre la atención Nursing formation and the drugs phenomenon in the South of Brazil: nursing students' attitudes and beliefs on care

Revista Latino-Americana de Enfermagem, 2005
Pesquisa descritiva sobre a formação do enfermeiro e sua relação com o fenômeno das drogas, realizada com alunos do último período de Graduação em Enfermagem de cinco Instituições Federais de Ensino Superior do sul do Brasil.
Telma Elisa Carraro, Goolan Hussein Rassool, Margarita Antonia Villar Luis   +2 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Prevalence Estimates for Pharmacological Neuroenhancement in Austrian University Students: Its Relation to Health-Related Risk Attitude and the Framing Effect of Caffeine Tablets

Frontiers in Pharmacology, 2018
Background: Pharmacological neuroenhancement (PN) is defined as the use of illicit or prescription drugs by healthy individuals for cognitive-enhancing purposes.
Pavel Dietz, Pavel Dietz, Benedikt Iberl, Emanuel Schuett, Mireille van Poppel, Mireille van Poppel, Rolf Ulrich, Matteo Christian Sattler, Matteo Christian Sattler   +8 more
doaj   +1 more source

A Quantitative LC–MS/MS Method for the Detection of 16 Synthetic Cathinones and 10 Metabolites and Its Application to Suspicious Clinical and Forensic Urine Samples

Pharmaceuticals, 2022
Background: Synthetic cathinones currently represent one of the most predominant (sub)-classes of new psychoactive substance (NPS) in illicit drug markets.
Abdulaziz A. Aldubayyan, Erika Castrignanò, Simon Elliott, Vincenzo Abbate   +3 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

A formação do enfermeiro e o fenômeno das drogas no estado do Rio de Janeiro - Brasil: atitudes e crenças La formación del enfermero y el fenómeno de las drogas en el estado de Rio de Janeiro - Brasil: actitudes y creencias Nursing formation and the drugs phenomenon in the state of Rio de Janeiro - Brazil: attitudes and beliefs

Revista Latino-Americana de Enfermagem, 2005
O presente estudo consistiu em identificar as atitudes e crenças em relação ao fenômeno das drogas, de alunos matriculados em cursos de graduação em Enfermagem de Universidade Pública do Rio de Janeiro (Brasil).
Gertrudes Teixeira Lopes, Margarita Antonia Villar Luis   +1 more
doaj   +1 more source

FORENSIC PSYCHIATRIC ASSESSMENT OF THE CRIMINAL AND CIVIL RESPONSIBILITY OF MENTALLY DISORDERED PERSONS [PDF]

The Egyptian Journal of Forensic Sciences and Applied Toxicology, 2018
Background:The psychiatric assessment of individuals involved in legal proceedings had significantly been advanced during the past decades. Aim of study: To estimate the prevalence of criminal and civil problems among mentally disordered persons ...
Ahmed Hamoda, Adel El-Zaid, Ayat Hemeda, Amal Ahmed, Safaa Eldabe   +4 more
doaj   +1 more source

Noticing and helping the neglected child: A Review of the literature [PDF]

, 2010
This report presents findings from a systematic literature review examining the evidence on the extent to which practicioners are equpped to recoconise and respond to the indicators that a child's needs are likely to be or are being neglected, whatever ...
Daniel, Brigid, Scott, J., Taylor, Julie, Barbour, M.   +3 more
core   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source