Results 251 to 260 of about 21,551,551 (367)

The MRGPRX2-substance P pathway regulates mast cell migration. [PDF]

open access: yesiScience
West PW   +6 more
europepmc   +1 more source

An antinociceptive role for substance P in acid-induced chronic muscle pain

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2011
Chia-Ching John Lin   +5 more
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Temperature-Dependent Trimethylamine N-Oxide Induced the Formation of Substance P Dimers. [PDF]

open access: yesJ Phys Chem B
Lantz C   +5 more
europepmc   +1 more source

Modulation of basal and stress‐induced amygdaloid substance P release by the potent and selective NK1 receptor antagonist L‐822429

open access: green, 2008
Nicolas Singewald   +9 more
openalex   +2 more sources

Substance P signaling mediates BMP‐dependent heterotopic ossification

open access: yesJournal of Cellular Biochemistry, 2011
Li-xin Kan   +11 more
semanticscholar   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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