Results 51 to 60 of about 2,039,151 (340)
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Studies on the syntheses of β-carboline alkaloids brevicarine and brevicolline
A new total synthesis of the β-carboline alkaloid brevicarine is disclosed. The synthesis was carried out starting from an aromatic triflate key intermediate, allowing the introduction of various substituents into position 4 of β-carboline by cross ...
Benedek Batizi +6 more
doaj +1 more source
Yiming Zhu, 1 Zuochao Yao, 2 Yushu Liu, 3 Wen Zhang, 2 Lele Geng, 2 Tao Ni 2 1Department of General Surgery, Shanghai Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Huangpu, Shanghai, China; 2Department of Plastic and
Zhu Y +5 more
doaj
Li Y, Wu J, Lu Q, et al. Int J Nanomedicine. 2022;17:2559-2575. The authors have advised that an error was made during the preparation of the Masson trichromatic staining tumor tissue images shown in Figure 7G on page 2570.
Li Y +10 more
doaj
We investigated the long-lasting effect of peripheral injection of the neuropeptide substance P (SP) and of some N- or C-terminal SP fragments (SPN and SPC, respectively) on retention test performance of avoidance learning. Male Wistar rats (220 to 280 g)
C. Tomaz, A.C.F. Silva, P.J.C. Nogueira
doaj +1 more source
Substance P Regulation in Epilepsy [PDF]
Epilepsy is a common neurological disease characterized by abnormal temporary discharge of neurons in the central nervous system. In recent years, studies have revealed the localization and changes in the density of neuropeptides, such as substance P (SP) in the pathogenesis of epilepsy. This review is a concise overview of SP and their physiologic and
Guangfan Chi +4 more
openaire +3 more sources
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Effect of self-esteem in the relationship between stress and substance abuse among adolescents: A mediation outcome [PDF]
The present study assessed the mediating effect of self-esteem in the relationship between stress and substance abuse among adolescents. The participants of the study were 352 adolescents, 54.5% males and 45.5% females aged 13 to18 years, from ...
Ikechukwu, Uba +4 more
core +1 more source
Mechanism of action of substance P [PDF]
Synthetic substance P (SP) raises glycine levels both in the brain and in the spinal cord. The synthetic polypeptide, as well as the single amino acid, abolishes motor hyperactivity induced by β,β′-iminodipropionitrile in mice. The amino acid is effective event at very low intrinsic glycine levels, a condition where the polypeptide fails to act.
M. Stern, Sabira Ćatović, P. Stern
openaire +3 more sources
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source

