Results 51 to 60 of about 2,039,151 (340)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Studies on the syntheses of β-carboline alkaloids brevicarine and brevicolline

open access: yesBeilstein Journal of Organic Chemistry
A new total synthesis of the β-carboline alkaloid brevicarine is disclosed. The synthesis was carried out starting from an aromatic triflate key intermediate, allowing the introduction of various substituents into position 4 of β-carboline by cross ...
Benedek Batizi   +6 more
doaj   +1 more source

Incorporation of ROS-Responsive Substance P-Loaded Zeolite Imidazolate Framework-8 Nanoparticles into a Ca2+-Cross-Linked Alginate/Pectin Hydrogel for Wound Dressing Applications

open access: yesInternational Journal of Nanomedicine, 2020
Yiming Zhu, 1 Zuochao Yao, 2 Yushu Liu, 3 Wen Zhang, 2 Lele Geng, 2 Tao Ni 2 1Department of General Surgery, Shanghai Ninth People’s Hospital, School of Medicine, Shanghai Jiao Tong University, Huangpu, Shanghai, China; 2Department of Plastic and
Zhu Y   +5 more
doaj  

GA&HA-Modified Liposomes for Co-Delivery of Aprepitant and Curcumin to Inhibit Drug-Resistance and Metastasis of Hepatocellular Carcinoma [Corrigendum]

open access: yesInternational Journal of Nanomedicine, 2022
Li Y, Wu J, Lu Q, et al. Int J Nanomedicine. 2022;17:2559-2575. The authors have advised that an error was made during the preparation of the Masson trichromatic staining tumor tissue images shown in Figure 7G on page 2570.
Li Y   +10 more
doaj  

Long-lasting mnemotropic effect of substance P and its N-terminal fragment (SP1-7) on avoidance learning

open access: yesBrazilian Journal of Medical and Biological Research, 1997
We investigated the long-lasting effect of peripheral injection of the neuropeptide substance P (SP) and of some N- or C-terminal SP fragments (SPN and SPC, respectively) on retention test performance of avoidance learning. Male Wistar rats (220 to 280 g)
C. Tomaz, A.C.F. Silva, P.J.C. Nogueira
doaj   +1 more source

Substance P Regulation in Epilepsy [PDF]

open access: yesCurrent Neuropharmacology, 2017
Epilepsy is a common neurological disease characterized by abnormal temporary discharge of neurons in the central nervous system. In recent years, studies have revealed the localization and changes in the density of neuropeptides, such as substance P (SP) in the pathogenesis of epilepsy. This review is a concise overview of SP and their physiologic and
Guangfan Chi   +4 more
openaire   +3 more sources

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Effect of self-esteem in the relationship between stress and substance abuse among adolescents: A mediation outcome [PDF]

open access: yes, 2013
The present study assessed the mediating effect of self-esteem in the relationship between stress and substance abuse among adolescents. The participants of the study were 352 adolescents, 54.5% males and 45.5% females aged 13 to18 years, from ...
Ikechukwu, Uba   +4 more
core   +1 more source

Mechanism of action of substance P [PDF]

open access: yesNaunyn-Schmiedeberg's Archives of Pharmacology, 1974
Synthetic substance P (SP) raises glycine levels both in the brain and in the spinal cord. The synthetic polypeptide, as well as the single amino acid, abolishes motor hyperactivity induced by β,β′-iminodipropionitrile in mice. The amino acid is effective event at very low intrinsic glycine levels, a condition where the polypeptide fails to act.
M. Stern, Sabira Ćatović, P. Stern
openaire   +3 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

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