Results 101 to 110 of about 2,260,368 (324)

Community context and individual factors associated with arrests among young men in a South African township. [PDF]

, 2019
BackgroundIn high-income countries, individual- and community-level factors are associated with increased contact with the criminal justice system. However, little is known about how these factors contribute to the risk of arrest in South Africa, which ...
Bantjes, Jason, Christodoulou, Joan, Gordon, Sarah, Mayekiso, Andile, Rabie, Stephan, Rotheram-Borus, Mary Jane, Stewart, Jackie, Stokes, Lynissa R, Tomlinson, Mark   +8 more
core   +3 more sources

Criminality among Young People With Substance Use Problems in Sweden: A One-Year Follow-Up Study [PDF]

, 2022
Mats Anderberg, Mikael Dahlberg, Peter Wennberg   +2 more
openalex   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Fentanyl assisted treatment: a possible role in the opioid overdose epidemic?

Substance Abuse Treatment, Prevention, and Policy, 2019
Background The current opioid overdose epidemic affecting communities across North America is increasingly driven by illicitly manufactured fentanyl and its related analogues.
Geoff Bardwell, Evan Wood, Rupinder Brar
doaj   +1 more source

Studies on the growth hormone of plants VII. The fate of growth substance in the plant and the nature of the growth process [PDF]

, 1935
Since the early work of Went (1928), it has been known that the growth substance of the Avena coleoptile may be obtained in the usual way, i.e. by diffusion into agar blocks, only from that part of the plant which produces it, namely the tip. The hormone
Bonner, James, Thimann, Kenneth V.
core   +2 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Implementation opportunities and challenges identified by key stakeholders in scaling up HIV Treatment as Prevention in British Columbia, Canada: a qualitative study

Implementation Science Communications, 2020
Background The province of British Columbia (BC), Canada, was among the first jurisdictions to scale up HIV Treatment as Prevention (TasP) to the population level, including funding and policy commitments that enhanced HIV testing efforts (e.g ...
Koharu Loulou Chayama, Ryan McNeil, Jean Shoveller, Will Small, Rod Knight   +4 more
doaj   +1 more source

Licit and illicit drug use across trimesters in pregnant women endorsing past-year substance use: Results from National Survey on Drug Use and Health (2009–2019)

, 2022
MacKenzie R. Peltier, Walter Roberts, Terril L. Verplaetse, Catherine Burke, Yasmin Zakiniaeiz, Kelly E. Moore, Sherry A. McKee   +6 more
openalex   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Is fentanyl in everything? Examining the unexpected occurrence of illicit opioids in British Columbia’s drug supply

Harm Reduction Journal
Background Illicit opioids, including fentanyl, are linked to unprecedented levels of overdose in Canada and elsewhere. The risks associated with illicit opioids can include high potency, unpredictable concentration and the unexpected presence in other ...
Bruce Wallace, Irene Shkolnikov, Collin Kielty, Derek Robinson, Lea Gozdzialski, Joshua Jai, Ava Margolese, Pablo Gonzalez-Nieto, Armin Saatchi, Lucas Abruzzi, Taelor Zarkovic, Chris Gill, Dennis Hore   +12 more
doaj   +1 more source