Results 101 to 110 of about 53,254,105 (402)

Involuntary discharge from drug or alcohol treatment programs in Vancouver, Canada

Harm Reduction Journal
Background Retention in substance use treatment is essential to treatment success. While programmatic factors are known to influence retention, less is known about the role of involuntary discharges from drug or alcohol treatment programs.
Kat Gallant, Kanna Hayashi, JinCheol Choi, M-J Milloy, Thomas Kerr   +4 more
doaj   +1 more source

mHealth versus face-to-face: study protocol for a randomized trial to test a gender-focused intervention for young African American women at risk for HIV in North Carolina

BMC Public Health, 2018
Background Disparities in the prevalence of HIV persist in the southern United States, and young African American women have a disproportionate burden of HIV as compared with young women of other racial/ethnic backgrounds.
Felicia A. Browne, Wendee M. Wechsberg, Paul N. Kizakevich, William A. Zule, Courtney P. Bonner, Ashton N. Madison, Brittni N. Howard, Leslie B. Turner   +7 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Barriers and facilitators to injectable opioid agonist treatment engagement within a structural vulnerability context: a qualitative study of patient experiences in Vancouver, Canada

Harm Reduction Journal
Background Amidst a sustained drug poisoning crisis, there is growing recognition in Canada of the need to expand injectable opioid agonist treatment (iOAT).
Samara Mayer, Nadia Fairbairn, Al Fowler, Jade Boyd, Thomas Kerr, Ryan McNeil   +5 more
doaj   +1 more source

Knowledge and possession of take-home naloxone kits among street-involved youth in a Canadian setting: a cohort study

Harm Reduction Journal, 2017
Background The distribution of take-home naloxone (THN) kits has been an important strategy in reducing overdose fatalities among people who use drugs. However, little is known about the use of THN among youth who are street-involved.
Julia Goldman-Hasbun, Kora DeBeck, Jane A. Buxton, Ekaterina Nosova, Evan Wood, Thomas Kerr   +5 more
doaj   +1 more source

Interpersonal relationships and drug use over time among homeless people: a qualitative study

BMC Public Health, 2020
Background Homelessness is one of the most severe forms of social exclusion and is an important public health issue. It is characterized by processes of weakening of interpersonal bonds.
Marília Ignácio de Espíndola, André Bedendo, Eroy Aparecida da Silva, Ana Regina Noto   +3 more
doaj   +1 more source

Young substance use and substance use disorder in Chile: the role of the family [PDF]

, 2021
As in other countries, Chilean youth-based treatments for justice-involved youths with substance use disorders need to find ways to obtain better results. One possibility is to involve family members in the intervention, thus we investigated family risk and protective factors for Chilean adolescents' substance use and substance use disorders.
openaire   +3 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Studies on the growth hormone of plants VII. The fate of growth substance in the plant and the nature of the growth process [PDF]

, 1935
Since the early work of Went (1928), it has been known that the growth substance of the Avena coleoptile may be obtained in the usual way, i.e. by diffusion into agar blocks, only from that part of the plant which produces it, namely the tip. The hormone
Bonner, James, Thimann, Kenneth V.
core   +2 more sources

The association between perceived stigma and substance use disorder treatment outcomes: a review

Substance Abuse and Rehabilitation, 2018
Substance use disorders (SUDs) take a heavy toll on those who have them and on society more broadly. These disorders are often difficult to treat, and relapse is common. Perhaps, because of these factors, these disorders are highly stigmatized worldwide.
K. Crapanzano, Rebecca Hammarlund, Bilal Ahmad, Natalie Hunsinger, Rumneet Kullar   +4 more
semanticscholar   +1 more source