Results 241 to 250 of about 53,729,253 (423)

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Substance P Radioimmunoassay Using N<SUP>α</SUP>-Tyrosyl-substance P and Demonstration of the Presence of Substance P-like Immunoreactivities in Human Blood and Porcine Tissue Extracts

, 1976
Chizuko Yanaihara, Haruko Sato, M Hirohashi, Masanori Sakagami, Kōichi Yamamoto, Tadashi Hashimoto, Noboru Yanaihara, Kaoru Abe, Toshio Kaneko   +8 more
openalex   +2 more sources

Influence of Parent–Youth Relationship, Parental Monitoring, and Parent Substance Use on Adolescent Substance Use Onset

Journal of family psychology, 2018
Julie C. Rusby, J. Light, Ryann Crowley, E. Westling   +3 more
semanticscholar   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Hippocampus Functional Connectivity, Impulsivity, and Subsequent Substance Use. [PDF]

J Cell Neurosci
Assari S, Donovan A, Najand B, Akhlaghipour G, Mendez MF.   +4 more
europepmc   +1 more source

Use of psychoactive substances in three medical specialties: anaesthesia, medicine and surgery [PDF]

, 1994
I Lutsky, Margaret Hopwood, Stephen E. Abram, James M. Cerletty, Raymond G. Hoffman, John P. Kampine   +5 more
openalex   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Intestinal barrier damage caused by addictive substance use disorder. [PDF]

Eur J Med Res
Gao Y, Kong D, Sun JX, Ma ZX, Wang GQ, Ma XF, Sun L, Luo HY, Xu Y, Wang KH.   +9 more
europepmc   +1 more source

Screening for new nematocidal substances of microbial origin by a new method using the pine wood nematode.

, 1988
Kazuhiko Otoguro, Zhong‐Xun Liu, Keiko FUKUDA, Yin Li, YUZURU IWAI, Haruo Tanaka, Satoshi Ōmura   +6 more
openalex   +2 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source