Results 251 to 260 of about 53,729,253 (423)

Malnutrition in Substance Use Disorders: A Critical Issue in Their Treatment and Recovery. [PDF]

Healthcare (Basel)
García-Estrada J, Luquin S, Pesqueda-Cendejas K, Ruiz-Ballesteros AI, Campos-López B, Meza-Meza MR, Parra-Rojas I, González-Castañeda RE, Ramos-Lopez O, De la Cruz-Mosso U.   +9 more
europepmc   +1 more source

Studies on active substances in herbs used for Oketsu ("stagnant blood") in Chinese medicine. VI On the anticoagulative principle in Paeoniae Radix.

, 1987
Hitoshi Ishida, MIKI TAKAMATSU, Kuniro Tsuji, Takuo Kosuge   +3 more
openalex   +2 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Involuntary Treatment for Severe Substance Use Disorders - Issues, Evidence and Considerations for its Use. [PDF]

Can J Psychiatry
Fischer B, Hall W, Jutras-Aswad D, Le Foll B.   +3 more
europepmc   +1 more source

Toxicity assessments of chemical substances using primary culture of rat hepatocytes.

, 1986
Jin Fang, Yasuhisa Kitagawa, Shinsuke Ishikawa, Hiroyuki Yanagisawa, Katsuyuki Nakajima, Shigeo Manabe, Osamu Wada   +6 more
openalex   +2 more sources

A Meta-Analysis of Longitudinal Associations Between Substance Use and Interpersonal Attachment Security

Psychological bulletin, 2018
Catharine E. Fairbairn, D. Briley, Dahyeon Kang, R. C. Fraley, B. Hankin, T. Ariss   +5 more
semanticscholar   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Recovery housing for substance use disorder: a systematic review. [PDF]

Front Public Health
Vilsaint CL, Tansey AG, Hennessy EA, Eddie D, Hoffman LA, Kelly JF.   +5 more
europepmc   +1 more source

A760 PATIENTS WITH A SUBSTANCE ABUSE HISTORY CAN EFFECTIVELY USE PCA [PDF]

, 1990
Brett R. Stacey, Michael C. Brody, DR Burke   +2 more
openalex   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source