Results 131 to 140 of about 1,878,278 (369)

Substance Use Disorder Treatment Decision Aid for Adults in Chittenden County Vermont [PDF]

, 2019
Substance Abuse Disorders (SUDs) are a prevalent public health concern in both the national and local arena resulting in millions of dollars in pubic health costs and loss of life.
McLeod, Elizabeth V
core   +1 more source

Substance Use Disorder in the CRNA [PDF]

, 2022
Substance use disorder (SUD) affects the anesthesia community disproportionally as compared to the general public (Rupprecht, 2022). It is estimated that SUD will affect 10%-15% of all anesthesia providers at some point in their careers (Rupprecht, 2022).
Hayes, Bridget
core   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Children of parents with substance abuse disorders had higher rates of conduct disorder and substance use [PDF]

, 1999
Lee Baldwin
openalex   +1 more source

Identifying components of recovery capital that support substance use disorder treatment completion

Addictive Behaviors Reports
Purpose: Individuals who do not complete substance use disorder treatment (SUDT) have similar outcomes to the untreated. Recovery capital (RC) is the collection of one’s resources that contribute to the initiation and maintenance of sobriety.
Ronald J. Headid, Trevor C. Doane, Brett D. Cohen, Emma C. Smith, David Redden, Alexis M. Stoner   +5 more
doaj  

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

A Bayesian Learning Model for Joint Risk Prediction of Alcohol and Cannabis Use Disorders [PDF]

arXiv
Substance use disorders (SUDs) are a serious public health concern in the United States. Alcohol and cannabis are two of the most widely used substances. For adolescent/youth users of alcohol or cannabis, we propose a joint Bayesian learning model to predict their risks of developing alcohol use disorder (AUD) and cannabis use disorder (CUD) in ...
arxiv  

Guidelines focus on common substance-use disorders [PDF]

, 1996

openalex   +1 more source

Investigating Chronic Illness in Pathways to Housing Clients [PDF]

, 2020
Approximately 553,000 individuals were homeless in the US each night in 2017, each at significant risk for substance use disorder, severe mental illness, and untreated chronic disease.
Malerich, Joshua, Weinstein, MD, DPH, Lara   +1 more
core   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source