Results 111 to 120 of about 15,613,357 (259)

Governor's Council on Substance Use Disorder - October 21, 2025 [PDF]

Downloaded from: https://www.nj.gov/gcsud/gcsud/agendas-minutes/ Agenda and minutes are in separate ...
New Jersey. Governor's Council on Substance Use Disorder
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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Governor's Council on Substance Use Disorder - April 16, 2024

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New Jersey. Governor's Council on Substance Use Disorder
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Canadian Institute for Substance Use Research Annual Report 2019-2020 [PDF]

, 2020
FacultyUnreviewe
Canadian Institute for Substance Use Research (CISUR)
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Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Governor's Council on Substance Use Disorder - March 19, 2024

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New Jersey. Governor's Council on Substance Use Disorder
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USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Governor's Council on Substance Use Disorder - October 15, 2024

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New Jersey. Governor's Council on Substance Use Disorder
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Substance Use Disorder Privacy Law Limits Both Payers, Prescribers

, 2017
We should reform or align 42 CFR Part 2 with HIPAA to better serve patients with substance use disorder, UMass Medical School pharmacists Kimberly Lenz and Tyson Thompson write in an opinion piece for Managed Healthcare ...
Lenz, Kimberly J., Thompson, Tyson
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Clinical strategies for low-dose overlap initiation of buprenorphine and potential barriers to use [PDF]

Mental Health Clinician
Austin Smith, PharmD, BCPP, Kaitlyn Weslosky, PharmD, BCPP, Ashley Haynes, MD, December Crew, PharmD   +3 more
doaj   +1 more source