Results 91 to 100 of about 639,012 (296)
SAGE Open MedicineBackground: Pharmacists are healthcare professionals who frequently encounter individuals struggling with addiction in their day-to-day practice. Studies critique pharmacists’ competence in the detection, prevention, and management of substance use ...
Ehab Mudher Mikhael +3 more
doaj +1 more source
Substance use and conduct disorders are common amongarrested North American Indigenous youth and increase theirlikelihood of arrest [PDF]
, 2016 In North America, substance misuse is very common among young people involved with the juvenile justice system, and even more so among American Indian and Canadian First Nations youth. In new research, Kelley J.
Sittner, Kelley J.
core
Impulsivity, Rejection Sensitivity, and Reactions to Stressors in Borderline Personality Disorder
, 2016 This research investigated baseline impulsivity, rejection sensitivity, and reactions to stressors in individuals with borderline personality disorder compared to healthy individuals and those with avoidant personality disorder .
Berenson, Kathy R. +6 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Preventive Medicine Reports, 2015 Objective: We aim to examine the relationships between substance use disorders and preventable hospitalizations for Ambulatory Care Sensitive Conditions among adult Medicaid beneficiaries.
Kit Sang Leung +2 more
doaj +1 more source
Frequency of Parental Psychopathology in Children with Attention Deficit Hyperactivity Disorder [PDF]
, 2012 Parental mental health concerns place children at a significantly greater risk of lower social, psychological and physical health than children in families not affected by mental illness.
Bhat, SM, Latha, KS, Nair, RB
core +1 more source
A Closer Look at Exclusion Criteria in Randomized Controlled Psychotherapy Trials for Adult Depression [PDF]
, 2020 A common concern regarding clinical trials evaluating treatments for depression is findings may not generalize to the population of interest due to the use of restrictive exclusion criteria.
Schenk, Anneliese
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Cariprazine in Bipolar Disorder and Substance Use: A Dual Approach to Treatment?
PharmaceuticalsBipolar disorder (BD) is characterized by recurrent episodes of mania, hypomania, and depression and is often complicated by comorbid substance use disorders (SUDs).
Simone Pardossi +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source