Results 41 to 50 of about 639,012 (296)

Error-related brain activity as a transdiagnostic endophenotype for obsessive-compulsive disorder, anxiety and substance use disorder [PDF]

, 2019
Background Increased neural error-signals have been observed in obsessive-compulsive disorder (OCD), anxiety disorders, and inconsistently in depression. Reduced neural error-signals have been observed in substance use disorders (SUD). Thus, alterations
Bey, Katharina, Grützmann, Rosa, Heinzel, Stephan, Kathmann, Norbert, Kaufmann, Christian, Klawohn, Julia, Lennertz, Leonhard, Riesel, Anja Riesel, Wagner, Michael   +8 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Supporting the wounded: Parents of adolescents recovering from substance use disorder

Health SA Gesondheid: Journal of Interdisciplinary Health Sciences
Background: The increase of adolescent substance use disorders (SUDs) around the world has a lot of negative effects on the parents and frequently degrades their quality of life. Substance use disorder is a critical issue recognised as a chronic, complex
Faith Mathibela, Jan Masombuka
doaj   +1 more source

Comorbidity of psychotic disorder and substance use disorder in a psychiatry inpatient unit: A retrospective study [PDF]

Klinik Psikiyatri Dergisi, 2018
Objective: Comorbidity of psychotic disorder and substance use disorder is common. Studies demonstrate that this comorbidity constitutes a major mental health problem.
Ebru Aldemir, Umut Baklaci, Ali Saffet Gonül   +2 more
doaj   +1 more source

Does Gender Moderate the Relationship Between Chronic Pain and Substance Use Disorder? Insights From a National Canadian Population Survey

Frontiers in Psychiatry, 2022
BackgroundThough it has been shown that men have a higher lifetime prevalence of substance use disorder and a lower prevalence of chronic pain than women, there is little research to date focusing on gender differences in the relationship between chronic
Yingying Su, Yingying Su, Xiangfei Meng, Carl D'Arcy, Carl D'Arcy   +4 more
doaj   +1 more source

Identifying Early Warning Signs: Addressing Youth Substance Use [PDF]

, 2015
Of high school students 35 percent indicate they are current drinkers, 20 percent are binge drinkers, and 24 percent use marijuana. By the time they are seniors more than 20 percent will have used a prescription drug for a nonmedical purpose.

core  

Attachment and emotion regulation in substance addictions and behavioral addictions [PDF]

, 2017
Background Risky behaviors have been related to emotional regulation and attachment, which may constitute risk factors for developing an addictive behavior. However, there may also be differences between substance and non-substance-related addictions.
Estévez, A, Griffiths, MD, Jáuregui, P, López-González, H, Sánchez-Marcos, I   +4 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A state-level study of opioid use disorder treatment access and neonatal abstinence syndrome [PDF]

, 2019
Background Adult opioid use and neonatal abstinence syndrome (NAS) are growing public health problems in the United States (U.S.). Our objective was to determine how opioid use disorder treatment access impacts the relationship between adult opioid use ...
Abbinanti, Kassie, Krist, Alex H., Pecsok, James, Sabo, Roy T., Tong, Sebastian T., Wolf, Elizabeth R., Woolf, Steven H.   +6 more
core   +1 more source

The Iowa Gambling Task and the three fallacies of dopamine in gambling disorder [PDF]

, 2013
Gambling disorder sufferers prefer immediately larger rewards despite long term losses on the Iowa Gambling Task (IGT), and these impairments are associated with dopamine dysfunctions.
Linnet, Jakob
core   +1 more source