Results 51 to 60 of about 15,613,357 (259)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Mental health and substance use problems among patients in substance use disorder treatment as reported by patients versus treatment personnel [PDF]

open access: yes, 2015
Objective: We examined and compared mental health and substance use problems among patients in substance use disorder treatment as reported by both patients and treatment personnel, and explored the feasibility of the quadrant model in addressing ...
Gråwe, R.W., Hagen, R., Bergly, T.H.
core   +1 more source

Disorders Due to Substance Use: Cannabis

open access: yes, 2023
Cannabis has a long history of use for its psychoactive properties but is a relative newcomer to the Western world as an intoxicant. Nowadays, cannabis is widely used and it causes serious problems in a minority of those who use it. However, given the large numbers of people who use cannabis, that relative minority translates into a substantial ...
Cousijn, J., Compton, W.M., Levin, F.R.
openaire   +5 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Treating substance abuse is not enough: Comorbidities in consecutively admitted female prisoners [PDF]

open access: yes, 2015
Publisher Copyright: © 2015 Elsevier Ltd.Introduction: Several studies have pointed to high rates of substance use disorders among female prisoners. The present study aimed to assess comorbidities of substance use disorders with other mental disorders in
Ströhle, Andreas   +11 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Substance use disorder risk assessment: positive emotional experiences with first time use and substance use disorder risk

open access: yesFrontiers in Psychiatry
IntroductionSubstance Use Disorder (SUD) screening tools used in current practice are designed to identify SUD once patients have begun regular dangerous drug use.
Karen E. Arscott   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Concerned parents, belligerent adolescent: Providing support to distressed parents

open access: yesIndian Journal of Social Psychiatry, 2018
Societal changes have brought about transformation in the family dynamics in India. The youth of today is exposed to a wide variety of influences, and their tendency toward experimentation makes them vulnerable to get into unpleasant situations.
Siddharth Sarkar
doaj   +1 more source

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