Results 131 to 140 of about 107,475 (276)

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

Chronic Diseases and Translational Medicine, EarlyView.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy, Cornelius J. Fernandez, Mohammad Hamid Nedai, Joseph M. Pappachan   +3 more
wiley   +1 more source

Use of cannabis in pregnancy and as a new parent [PDF]

The most common illicit drug used by women of reproductive age and by pregnant women is cannabis (DrugInfo, 2005). Although there are limited national data available on illicit substance use among parents in Australia, the 2007 National Drug Strategy ...
Centre for Community Child Health
core  

As Opioid Use Climbs, Neonatal Abstinence Syndrome Rises in New Hampshire [PDF]

, 2017
In this brief, author Kristin Smith analyzes inpatient hospital discharge data (2012–2015) to assess the prevalence of neonatal abstinence syndrome (NAS) in New Hampshire; describes one hospital’s successful program for treating pregnant women and ...
Smith, Kristin
core   +1 more source

Asymmetric Reduction of Unactivated Alkenes

Chemistry – A European Journal, EarlyView.
Unactivated alkenes rank among the most inert functional groups in synthesis and their selective reduction remains challenging. This Review charts the evolution from classical metal‐catalyzed hydrogenation to radical hydrogen atom transfer (HAT) and emerging biocatalytic concepts, highlighting how complementary mechanistic strategies, including the ...
Nico D. Fessner, Sebastian Roth, Richard Niese, Michael Müller   +3 more
wiley   +1 more source

Social Comparison and Its Association With Disordered Eating Symptoms: A Systematic Review and Meta‐Analysis

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Social comparison has been widely implicated in the etiology and maintenance of body dissatisfaction and eating disorders. At the same time, however, the magnitude of this relationship remains unclear, with existing studies varying widely in methodology, measurement, and sample characteristics.
Fidan Turk, Aysesu Bozdogan, Rachel Hughes, Phaedra Longhurst, Millie Chilvers, Ellen E. Fitzsimmons‐Craft   +5 more
wiley   +1 more source

Clinical presentation and treatment in kratom withdrawal: a narrative review of case studies

Journal of Education, Health and Sport
Background. Kratom (Mitragyna speciosa) use is increasing internationally and case reports describe a range of withdrawal syndromes. Clinical guidance for recognizing and managing kratom withdrawal is limited.
Wojciech Baran, Patrycja Bartkiewicz, Ewelina Lachowska, Tomasz Jędrasek, Adrian Korman, Wafa Al-Batool   +5 more
doaj   +1 more source

Inroads into epilepsy through high‐frequency oscillations: Achievements and benchmark areas for improvement

Epilepsia, EarlyView.
Abstract High‐frequency oscillations (HFOs) were discovered more than 20 years ago, and since then they have been studied intensively in the context of epilepsy. HFOs encompass a broad spectrum of oscillations, typically ranging from 80 Hz to several kHz, that include both normal and pathological oscillations, documented in people with epilepsy and ...
Christos Panagiotis Lisgaras, Birgit Frauscher, Jean Gotman, Julia Jacobs, Philippe Kahane, Richard J. Staba, Maeike Zijlmans   +6 more
wiley   +1 more source

Validation of an instrument to evaluate the signs and symptoms of benzodiazepine withdrawal

Revista Contexto & Saúde
Objective: to develop and validate an instrument to evaluate signs and symptoms that may occur during the process of deprescribing benzodiazepines in elderly Brazilian people.
Marlon Silva Tinoco, Letícia Maria Ribeiro, Ricardo Augusto dos Santos Silva, Luciana Soares Rodrigues, Luanna Gabriella Resende da Silva, Mariana Linhares Pereira, André Oliveira Baldoni   +6 more
doaj   +1 more source

Continuous outcome estimation in N‐of‐1 trials for accelerated decision‐making

Epilepsia, EarlyView.
Abstract Objective N‐of‐1 trials aim to determine the therapeutic effect for a single individual. This individualized approach necessitates collecting multiple data points over time through repeated alternating periods of active treatment and a comparator or control condition.
Victoria Defelippe, František Bartoš, Eric‐Jan Wagenmakers, Kees P. J. Braun, Floor E. Jansen, Willem M. Otte   +5 more
wiley   +1 more source

Dezocine modulates the reinstatement of conditioned place preference in morphine-dependent rats via the dopamine reward circuitry

Frontiers in Neuroscience
IntroductionOpioid addiction is a significant public health issue, with existing treatments such as buprenorphine and methadone exhibiting limitations, including side effects and insufficient prevention of relapse. Novel therapeutic strategies are needed
Yan He, Yan He, Zhi-Sheng Piao, Yi Jia, Hui-Qi Wu, Xiao-Qiang Wang, Xiao-Qiang Wang, Wei-Feng Yu, Wei-Feng Yu, Wei-Feng Yu, Fei-Xiang Wu, Fei-Xiang Wu   +11 more
doaj   +1 more source